EGF signalling amplification induced by dynamic clustering of EGFR.
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Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interfaceMembrane microdomains: from seeing to understandingSingle Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated PitsBreast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment.Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution.Time-resolved multimodal analysis of Src Homology 2 (SH2) domain binding in signaling by receptor tyrosine kinasesVinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface.Single-molecule analysis of epidermal growth factor binding on the surface of living cells.Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.Manipulating the lateral diffusion of surface-anchored EGF demonstrates that receptor clustering modulates phosphorylation levelsEGFR oligomerization organizes kinase-active dimers into competent signalling platformsMicroscopic simulation of membrane molecule diffusion on corralled membrane surfaces.Sphingolipids are involved in N-methyl-N'-nitro-N-nitrosoguanidine-induced epidermal growth factor receptor clustering.Ligand-induced homotypic and heterotypic clustering of apolipoprotein E receptor 2Optical sizing of immunolabel clusters through multispectral plasmon coupling microscopyEpidermal growth factor receptor activation remodels the plasma membrane lipid environment to induce nanocluster formation.Measuring EGFR separations on cells with ~10 nm resolution via fluorophore localization imaging with photobleaching.Propranolol restricts the mobility of single EGF-receptors on the cell surface before their internalizationEffect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM.ErbB1 dimerization is promoted by domain co-confinement and stabilized by ligand binding.Oligomerization of the EGF receptor investigated by live cell fluorescence intensity distribution analysis.Epidermal growth factor-stimulated Akt phosphorylation requires clathrin or ErbB2 but not receptor endocytosisPlasma Membrane Organization of Epidermal Growth Factor Receptor in Resting and Ligand-Bound States.Current challenges in quantitative modeling of epidermal growth factor signaling.Evaluating the Raftophilicity of Rhodopsin Photoreceptor in a Patterned Model Membrane.An electrostatic engine model for autoinhibition and activation of the epidermal growth factor receptor (EGFR/ErbB) familyExploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach.Immobilized epidermal growth factor stimulates persistent, directed keratinocyte migration via activation of PLCγ1Alpha6beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancerA fluid membrane-based soluble ligand-display system for live-cell assays.Activation-Dependent Rapid Postsynaptic Clustering of Glycine Receptors in Mature Spinal Cord Neurons.In situ single molecule imaging of cell membranes: linking basic nanotechniques to cell biology, immunology and medicine.Inhibiting EGFR clustering and cell proliferation with gold nanoparticles.Ligand binding induces a conformational change in epidermal growth factor receptor dimers.Predominance of activated EGFR higher-order oligomers on the cell surface.Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10.Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis.Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation.EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms.Enzymatic biomineralization of biocompatible CuInS2, (CuInZn)S2 and CuInS2/ZnS core/shell nanocrystals for bioimaging.
P2860
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P2860
EGF signalling amplification induced by dynamic clustering of EGFR.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
EGF signalling amplification induced by dynamic clustering of EGFR.
@en
type
label
EGF signalling amplification induced by dynamic clustering of EGFR.
@en
prefLabel
EGF signalling amplification induced by dynamic clustering of EGFR.
@en
P2093
P1476
EGF signalling amplification induced by dynamic clustering of EGFR
@en
P2093
Junya Ichinose
Masayuki Murata
Toshio Yanagida
P304
P356
10.1016/J.BBRC.2004.09.173
P50
P577
2004-11-01T00:00:00Z