Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide.
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Novel immunotherapies for hematologic malignanciesNew Insights into IDO Biology in Bacterial and Viral Infections.1-Methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activityInhibition of T cell proliferation by macrophage tryptophan catabolismExpression of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase in early conceptiBeyond Tryptophan Synthase: Identification of Genes That Contribute to Chlamydia trachomatis Survival during Gamma Interferon-Induced Persistence and ReactivationHypoxia modulates cyclin and cytokine expression and inhibits peripheral mononuclear cell proliferation.Redox reactions related to indoleamine 2,3-dioxygenase and tryptophan metabolism along the kynurenine pathway.Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cellsInhibition of collagenase and stromelysin gene expression by interferon-gamma in human dermal fibroblasts is mediated in part via induction of tryptophan degradation.Comprehensive metabolome analyses reveal N-acetylcysteine-responsive accumulation of kynurenine in systemic lupus erythematosus: implications for activation of the mechanistic target of rapamycinChanges in endogenous cytokines, adhesion molecules and platelets during cytokine-induced tumour necrosis.Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites.Temporal heterogeneity in microregional erythrocyte flux in experimental solid tumours.Cell cycle arrest by kynurenine in lens epithelial cells.Indoleamine 2,3-dioxygenase (IDO) is expressed at feto-placental unit throughout mouse gestation: An immunohistochemical studyStem cells ameliorate EAE via an indoleamine 2,3-dioxygenase (IDO) mechanismImaging correlates of differential expression of indoleamine 2,3-dioxygenase in human brain tumors.α-methyl-L-tryptophan: mechanisms for tracer localization of epileptogenic brain regions.As2O3 induces apoptosis in human hepatocellular carcinoma HepG2 cells through a ROS-mediated mitochondrial pathway and activation of caspasesExpression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activationLoss of STAT1 expression confers resistance to IFN-gamma-induced apoptosis in ME180 cells.Cytotoxic effect of tumour necrosis factor -alpha on sarcoma F cells at tumour relevant oxygen tensions.Microelectrode measurements of pericellular PO2 in erythropoietin-producing human hepatoma cell cultures.Cane molasses as a source of precursors in the bioproduction of tryptophan by Bacillus subtilis.Indoleamine 2, 3-dioxygenase (IDO) is essential for dendritic cell activation and chemotactic responsiveness to chemokines.In vivo uptake and metabolism of alpha-[11C]methyl-L-tryptophan in human brain tumors.
P2860
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P2860
Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Inhibition of tumor cell growt ...... tinamide adenine dinucleotide.
@en
type
label
Inhibition of tumor cell growt ...... tinamide adenine dinucleotide.
@en
prefLabel
Inhibition of tumor cell growt ...... tinamide adenine dinucleotide.
@en
P2860
P356
P1476
Inhibition of tumor cell growt ...... tinamide adenine dinucleotide.
@en
P2093
P2860
P304
P356
10.1172/JCI114247
P407
P577
1989-09-01T00:00:00Z