Core transcriptional regulatory circuitry in human hepatocytes.
about
Identification of an endogenous ligand bound to a native orphan nuclear receptorDifferential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seqGenome wide prediction of HNF4alpha functional binding sites by the use of local and global sequence contextMicroarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivativesThe transcriptional foundation of pluripotencyLet-7 and miR-200 microRNAs: guardians against pluripotency and cancer progressionGenome-wide location analysis reveals distinct transcriptional circuitry by paralogous regulators Foxa1 and Foxa2Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cellsStem cells, the molecular circuitry of pluripotency and nuclear reprogrammingUltrasensitive response motifs: basic amplifiers in molecular signalling networks.Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling.A bayesian framework that integrates heterogeneous data for inferring gene regulatory networksAlterations of epigenetic signatures in hepatocyte nuclear factor 4α deficient mouse liver determined by improved ChIP-qPCR and (h)MeDIP-qPCR assays.Cell cycle genes are the evolutionarily conserved targets of the E2F4 transcription factor.Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus.Genome-wide occupancy of SREBP1 and its partners NFY and SP1 reveals novel functional roles and combinatorial regulation of distinct classes of genesGenome-scale validation of deep-sequencing libraries.Multistable decision switches for flexible control of epigenetic differentiation.Computational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibilityGene set-based module discovery in the breast cancer transcriptome.Does negative auto-regulation increase gene duplicability?A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia.Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes.Identification of interacting transcription factors regulating tissue gene expression in humanNetworks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes.Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the ludwigshafen risk and cardiovascular health study).Integrative analysis of low- and high-resolution eQTLDirect reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAs.A quantitative model of transcriptional regulation reveals the influence of binding location on expressionFunctional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network.Nuclear receptor HNF4α binding sequences are widespread in Alu repeatsFoxa2 is essential for mouse endometrial gland development and fertility.Quantifying and analyzing the network basis of genetic complexitySynthetic mammalian transgene negative autoregulation.Cooperativity and rapid evolution of cobound transcription factors in closely related mammalsEnhancing the prioritization of disease-causing genes through tissue specific protein interaction networks.Genome-wide analysis of androgen receptor targets reveals COUP-TF1 as a novel player in human prostate cancer.Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.Role of hepatocyte nuclear factor 4α in controlling copper-responsive transcription.Models of human core transcriptional regulatory circuitries.
P2860
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P2860
Core transcriptional regulatory circuitry in human hepatocytes.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Core transcriptional regulatory circuitry in human hepatocytes.
@en
type
label
Core transcriptional regulatory circuitry in human hepatocytes.
@en
prefLabel
Core transcriptional regulatory circuitry in human hepatocytes.
@en
P2093
P2860
P50
P356
P1476
Core transcriptional regulatory circuitry in human hepatocytes.
@en
P2093
David K Gifford
Elizabeth S Jacobsen
Graeme I Bell
Lena Nekludova
P Alexander Rolfe
Richard A Young
Timothy W Danford
P2860
P304
P356
10.1038/MSB4100059
P577
2006-05-02T00:00:00Z