Lipoproteins, not lipopolysaccharide, are the key mediators of the proinflammatory response elicited by heat-killed Brucella abortus.
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Analyzing the molecular mechanism of lipoprotein localization in BrucellaUnlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteinsBrucella cyclic β-1,2-glucan plays a critical role in the induction of splenomegaly in mice.Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection.Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosisRegulation of the mitogen-activated protein kinases by Brucella spp. expressing a smooth and rough phenotype: relationship to pathogen invasiveness.An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infectionDeep-sequencing analysis of the mouse transcriptome response to infection with Brucella melitensis strains of differing virulence.Outer membrane vesicles from Brucella abortus promote bacterial internalization by human monocytes and modulate their innate immune response.Protective immunity elicited by a divalent DNA vaccine encoding both the L7/L12 and Omp16 genes of Brucella abortus in BALB/c mice.The Attenuated Brucella abortus Strain 19 Invades, Persists in, and Activates Human Dendritic Cells, and Induces the Secretion of IL-12p70 but Not IL-23Potential role of fibroblast-like synoviocytes in joint damage induced by Brucella abortus infection through production and induction of matrix metalloproteinases.Proteomic Profile of Brucella abortus-Infected Bovine Chorioallantoic Membrane Explants.CCL20 and Beta-Defensin 2 Production by Human Lung Epithelial Cells and Macrophages in Response to Brucella abortus Infection.Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development.Toll-like receptors are critical for clearance of Brucella and play different roles in development of adaptive immunity following aerosol challenge in miceBrucella spp noncanonical LPS: structure, biosynthesis, and interaction with host immune system.Modulation of the bovine trophoblastic innate immune response by Brucella abortus.A conserved and immunodominant lipoprotein of Francisella tularensis is proinflammatory but not essential for virulenceBrucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinasesGenomic island 2 of Brucella melitensis is a major virulence determinant: functional analyses of genomic islands.Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infectionInflammation impairs reverse cholesterol transport in vivo.Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella.Key role of Toll-like receptor 2 in the inflammatory response and major histocompatibility complex class ii downregulation in Brucella abortus-infected alveolar macrophages.The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection.An evolutionary strategy for a stealthy intracellular Brucella pathogen.The role of innate immune signals in immunity to Brucella abortus.Brucella melitensis triggers time-dependent modulation of apoptosis and down-regulation of mitochondrion-associated gene expression in mouse macrophages.Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-κB Ligand and Tumor Necrosis Factor Alpha SecretionLevels of interleukin-(IL)-12p40 are markedly increased in Brucellosis among patients with specific IL-12B genotypes.Brucella and Osteoarticular Cell Activation: Partners in Crime.Granulocyte-macrophage colony-stimulating factor- and tumor necrosis factor alpha-mediated matrix metalloproteinase production by human osteoblasts and monocytes after infection with Brucella abortus.Adrenal steroids modulate the immune response during Brucella abortus infection by a mechanism that depends on the regulation of cytokine production.Nucleotide-binding oligomerization domain-1 and -2 play no role in controlling Brucella abortus infection in mice.Effects of smoking on the ex vivo cytokine production in periodontitis.NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus.B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.TLR2 and AP-1/NF-kappaB are involved in the regulation of MMP-9 elicited by heat killed Listeria monocytogenes in human monocytic THP-1 cells.
P2860
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P2860
Lipoproteins, not lipopolysaccharide, are the key mediators of the proinflammatory response elicited by heat-killed Brucella abortus.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Lipoproteins, not lipopolysacc ...... heat-killed Brucella abortus.
@en
type
label
Lipoproteins, not lipopolysacc ...... heat-killed Brucella abortus.
@en
prefLabel
Lipoproteins, not lipopolysacc ...... heat-killed Brucella abortus.
@en
P2093
P1476
Lipoproteins, not lipopolysacc ...... heat-killed Brucella abortus.
@en
P2093
Astrid Zwerdling
Guillermo H Giambartolomei
Juliana Cassataro
Laura Bruno
Mario T Philipp
P304
P356
10.4049/JIMMUNOL.173.7.4635
P407
P577
2004-10-01T00:00:00Z