The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.
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The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onsetPrimary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammationFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesEndoplasmic Reticulum Stress Interacts With Inflammation in Human DiseasesChronic administration of AMD3100 increases survival and alleviates pathology in SOD1(G93A) mice model of ALSDoes neuroinflammation fan the flame in neurodegenerative diseases?Translational research involving oxidative stress and diseases of aging.An in vitro screening cascade to identify neuroprotective antioxidants in ALSInflammation in ALS and SMA: sorting out the good from the evil.Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.One universal common endpoint in mouse models of amyotrophic lateral sclerosis.Glycogen synthase kinase-3β inactivation inhibits tumor necrosis factor-α production in microglia by modulating nuclear factor κB and MLK3/JNK signaling cascadesProgress in therapy development for amyotrophic lateral sclerosisNordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male miceInflammation and neuronal death in the motor cortex of the wobbler mouse, an ALS animal model.A comparative review of cell culture systems for the study of microglial biology in Alzheimer's disease.Characterization of the Contribution of Genetic Background and Gender to Disease Progression in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis: A Meta-Analysis.Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D16-Mercaptopurine attenuates tumor necrosis factor-α production in microglia through Nur77-mediated transrepression and PI3K/Akt/mTOR signaling-mediated translational regulationRole of zinc in ALS.Increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease.Design of aging intervention studies: the NIA interventions testing program.Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis.Antioxidants in central nervous system diseases: preclinical promise and translational challenges.Recent developments in the inhibitors of neuroinflammation and neurodegeneration: inflammatory oxidative enzymes as a drug target.Natural compounds with anti-ageing activity.Longevity extension by phytochemicals.Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo.Effect of nordihydroguaiaretic acid on cell viability and glucose transport in human leukemic cell lines.Tumor necrosis factor alpha-mediated nitric oxide production enhances manganese superoxide dismutase nitration and mitochondrial dysfunction in primary neurons: an insight into the role of glial cells.Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation.Combined Analysis of Phenotypic and Target-Based Screening in Assay Networks.Current and emerging treatments for amyotrophic lateral sclerosis.Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis.Protection of mouse brain from aluminum-induced damage by caffeic acid.Alteration in inflammatory/apoptotic pathway and histone modifications by nordihydroguaiaretic acid prevents acute pancreatitis in swiss albino mice.Profile of Arachidonic Acid-Derived Inflammatory Markers and Its Modulation by Nitro-Oleic Acid in an Inherited Model of Amyotrophic Lateral Sclerosis.Essential fatty acids enhance free radical generation and lipid peroxidation to induce apoptosis of tumor cells
P2860
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P2860
The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The arachidonic acid 5-lipoxyg ...... of G93A-SOD1 transgenic mice.
@en
type
label
The arachidonic acid 5-lipoxyg ...... of G93A-SOD1 transgenic mice.
@en
prefLabel
The arachidonic acid 5-lipoxyg ...... of G93A-SOD1 transgenic mice.
@en
P2093
P2860
P1476
The arachidonic acid 5-lipoxyg ...... of G93A-SOD1 transgenic mice.
@en
P2093
Alex Ceballos
Charles Stewart
Frank Zemlan
Kelly S Williamson
Kenneth Hensley
Ladan Hamdheydari
Melinda West
Molina Mhatre
Paula Grammas
Quentin N Pye
P2860
P304
P356
10.1111/J.1471-4159.2004.02700.X
P407
P577
2004-10-01T00:00:00Z