Granzymes: exogenous proteinases that induce target cell apoptosis.
about
Perforin and granzyme B have separate and distinct roles during atherosclerotic plaque development in apolipoprotein E knockout miceNucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytesEvaluating the cytotoxicity of innate immune effector cells using the GrB ELISPOT assayThe Granzyme B ELISPOT assay: an alternative to the 51Cr-release assay for monitoring cell-mediated cytotoxicityPolarizing T and B Cell Responses by APC-Targeted Subunit VaccinesModulation of immune response by organophosphorus pesticides: fishes as a potential model in immunotoxicologyApoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastaseGranzyme M mediates a novel form of perforin-dependent cell deathThe Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32Systematic characterization of human CD8+ T cells with natural killer cell markers in comparison with natural killer cells and normal CD8+ T cellsDistinct T cell receptor signaling requirements for perforin- or FasL-mediated cytotoxicity.Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?Four serine proteinases expressed in Manduca sexta haemocytes.Regulation of pro-apoptotic leucocyte granule serine proteinases by intracellular serpins.NK cells and apoptosis.Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction.Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathwayThe relative role of lymphocyte granule exocytosis versus death receptor-mediated cytotoxicity in viral pathophysiologyFas ligand-mediated lysis of self bystander targets by human papillomavirus-specific CD8+ cytotoxic T lymphocytes.Solid tumor-targeted infiltrating cytotoxic T lymphocytes retained by a superantigen fusion proteinThe significance of apoptosis in the liver.The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.Human and mouse granzyme M display divergent and species-specific substrate specificities.Expression of cytotoxic proteins in peripheral T-cell and natural killer-cell (NK) lymphomas: association with extranodal site, NK or Tgammadelta phenotype, anaplastic morphology and CD30 expression.Lysosomal destabilization in p53-induced apoptosisDelivery and therapeutic potential of human granzyme B.Update on herpes virus infections of the nervous system.Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes.The major CD8 T cell effector memory subset in the normal and Chlamydia trachomatis-infected human endocervix is low in perforinPhytoncides (wood essential oils) induce human natural killer cell activity.Role of TNF family ligands in antitumor activity of natural killer cells.Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection.CD8⁺ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung.Targeted apoptosis activation with GrB/scFvMEL modulates melanoma growth, metastatic spread, chemosensitivity, and radiosensitivity.NKG2D⁺ IFN-γ⁺ CD8⁺ T cells are responsible for palladium allergyThe role of T cells in psoriasis.Evidence that intestinal intraepithelial lymphocytes are activated cytotoxic T cells in celiac disease but not in giardiasis.High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability.The cytotoxic cell protease granzyme B initiates apoptosis in a cell-free system by proteolytic processing and activation of the ICE/CED-3 family protease, CPP32, via a novel two-step mechanism.
P2860
Q21559543-E69B220D-50E7-4D39-9B0D-07309937822DQ24291464-E26AFBF7-4A8E-471D-ACCF-27E3C845873DQ24319054-842ED940-1819-4B21-BF1B-F10A897F9946Q24800129-ADFA9791-ADC4-4DE0-AC8F-ADFA8A975FBDQ24806953-DA7E4A3B-5237-45F4-A39E-35CBC66FF612Q26800145-E24B46CD-5A16-4524-8C1F-9B2BF5B31386Q26996785-1A12A646-6737-4293-ACBE-5715D336F892Q27478353-163ACD47-7B98-4920-A5B8-CB2EF07D3CD8Q28251140-652612A1-908D-4D4D-B489-319E2E5110F2Q28295448-B34CB227-ACA8-4677-B1A6-293330C40636Q28343871-265EC4AA-D6AC-4760-8B47-110F1D483584Q30442845-B87D1535-E00B-47B8-8AFE-B584A5468891Q30710689-C110B441-FB9D-47F1-A15D-14209E203849Q31917724-8400779F-2902-4FD7-8861-E14A6531813AQ33547789-94DE9777-C10C-4E2A-BD2E-EB30AE023CECQ33547794-7A06013E-D01D-4C72-807C-1A3424BB50FBQ33547796-0774454F-7D05-4B5E-8E1D-E7306BAFDA27Q33781431-03551D7E-4740-44BB-B591-D2B0656C9E4DQ33781851-F0388299-CECC-422F-85B8-C7A61E559971Q33785691-ABFBC836-901E-4297-8FAF-1DA765846539Q33818177-03050E5E-F70F-4CE1-AA07-42257A673658Q33830932-4E9E5773-210C-4C2D-856E-FCDE10B2791DQ33876972-6D3EEA92-B601-462E-BEDF-194FED01E704Q33896439-AE7D4FC7-A2D5-4921-BFAD-056460544257Q33929834-2FD54BB0-45FF-4C05-9F8A-915198B74A3FQ34028866-86093A82-FAB8-466C-8578-C40644A65BCAQ34120062-A0D39099-FE56-4407-886F-D11E138A060FQ34379006-ECE3322A-B608-4F50-84AB-6DACBBEA3272Q34422070-693457D3-9AF9-475D-9FC8-78E803F6F559Q34502654-34694E05-C3CD-4EAF-B95F-128D0FA25495Q34551738-BBDA83CF-54D6-43AE-A4FE-5D1DDC6F8D5BQ34552156-1AF4659E-DE80-4A0A-B50A-30AA06E6AFBFQ34937146-EDCD2D86-F6E6-45F7-BC84-3C8454AB6FE2Q35015677-BEA9663B-A031-4328-B85B-8A9C9B7E2E01Q35052161-59A9FFE5-FB92-4A9B-9D72-E13FB8C4BE12Q35095243-6B5B9FD5-5F8A-4FD9-B8A6-4D83D7B78ABEQ35110104-BC90F651-F250-4AEA-BFE7-526D4B39FF0EQ35773749-C6F185B8-ACE4-47B9-90CA-365213E73156Q35787046-CA8AD995-9749-4580-9571-6A893F7A702CQ35850116-81B440FC-2F06-457A-966B-89C7633A09B8
P2860
Granzymes: exogenous proteinases that induce target cell apoptosis.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Granzymes: exogenous proteinases that induce target cell apoptosis.
@en
type
label
Granzymes: exogenous proteinases that induce target cell apoptosis.
@en
prefLabel
Granzymes: exogenous proteinases that induce target cell apoptosis.
@en
P1433
P1476
Granzymes: exogenous proteinases that induce target cell apoptosis
@en
P2093
Trapani JA
P304
P356
10.1016/0167-5699(95)80122-7
P577
1995-04-01T00:00:00Z