Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli.
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A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replicationPolo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5AStructure of the zinc-binding domain of an essential component of the hepatitis C virus replicaseThe NS5A Protein of Bovine Viral Diarrhea Virus Contains an Essential Zinc-Binding Site Similar to That of the Hepatitis C Virus NS5A ProteinHepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteinsHepatitis C virus NS5A protein binds the SH3 domain of the Fyn tyrosine kinase with high affinity: mutagenic analysis of residues within the SH3 domain that contribute to the interactionRegulation of Hepatitis C Virion Production via Phosphorylation of the NS5A ProteinCrystal Structure of a Novel Dimeric Form of NS5A Domain I Protein from Hepatitis C VirusHepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and BInvolvement of FKBP6 in hepatitis C virus replicationHCV core residues critical for infectivity are also involved in core-NS5A complex formationSequence-Specific Fidelity Alterations Associated with West Nile Virus Attenuation in MosquitoesDEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5APhosphatidylinositol 4,5-bisphosphate is an HCV NS5A ligand and mediates replication of the viral genomeUltradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin.Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteinsRegulation of PKR by HCV IRES RNA: importance of domain II and NS5AExpanding the proteome of an RNA virus by phosphorylation of an intrinsically disordered viral protein.Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.Human mitochondrial RNA polymerase: evaluation of the single-nucleotide-addition cycle on synthetic RNA/DNA scaffolds.Over-expression and characterization of NS3 and NS5A of Hepatitis C virus genotype 3a.Identification of the oriI-binding site of poliovirus 3C protein by nuclear magnetic resonance spectroscopy.Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.A novel immuno-competitive capture mass spectrometry strategy for protein-protein interaction profiling reveals that LATS kinases regulate HCV replication through NS5A phosphorylation.Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication.Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family.TARGETING THE NS5A PROTEIN OF HCV: AN EMERGING OPTION.Hepatitis C virus NS5A protein modulates template selection by the RNA polymerase in in vitro system.Quantitative Evaluation of Viral Protein Binding to Phosphoinositide Receptors and Pharmacological Inhibition.The Casein Kinase 2-Dependent Phosphorylation of NS5A Domain 3 from Hepatitis C Virus Followed by Time-Resolved NMR Spectroscopy.Hepatitis C virus NS5A is a direct substrate of casein kinase I-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors.HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors.Insight into poliovirus genome replication and encapsidation obtained from studies of 3B-3C cleavage site mutants.Fed-batch cultivation of Escherichia coli expressed designer hepatitis C virus diagnostic intermediate and its evaluation.NS5A: a new target for antiviral drugs in the treatment of hepatitis C virus infection.The hepatitis C viral nonstructural protein 5A stabilizes growth-regulatory human transcripts.
P2860
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P2860
Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Purification and characterizat ...... expressed in Escherichia coli.
@en
type
label
Purification and characterizat ...... expressed in Escherichia coli.
@en
prefLabel
Purification and characterizat ...... expressed in Escherichia coli.
@en
P2093
P50
P1476
Purification and characterizat ...... expressed in Escherichia coli.
@en
P2093
Kevin D Raney
Luyun Huang
Mehul Suthar
Michele R S Hargittai
P304
P356
10.1016/J.PEP.2004.05.005
P577
2004-09-01T00:00:00Z