Myofibroblastic differentiation leads to hyaluronan accumulation through reduced hyaluronan turnover.
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A rapid transient increase in hyaluronan synthase-2 mRNA initiates secretion of hyaluronan by corneal keratocytes in response to transforming growth factor beta.Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.Hyaluronan as an immune regulator in human diseases.Involvement of hyaluronan in regulation of fibroblast phenotype.Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction.Peroxisome proliferator-activated receptor gamma ligands inhibit transforming growth factor-beta-induced, hyaluronan-dependent, T cell adhesion to orbital fibroblasts.The human hyaluronan synthase 2 (HAS2) gene and its natural antisense RNA exhibit coordinated expression in the renal proximal tubular epithelial cellThe extracellular matrix: an active or passive player in fibrosis?Hyaluronan Controls the Deposition of Fibronectin and Collagen and Modulates TGF-β1 Induction of Lung Myofibroblasts.Hyaluronan-dependent pericellular matrix.Hyaluronan as a therapeutic target in human diseasesHuman Recombinant Hyaluronidase Injections For Upper Limb Muscle Stiffness in Individuals With Cerebral Injury: A Case Series.Age-related changes in pericellular hyaluronan organization leads to impaired dermal fibroblast to myofibroblast differentiation.A modified ELISA accurately measures secretion of high molecular weight hyaluronan (HA) by Graves' disease orbital cells.Hyaluronan in wound healing: rediscovering a major player.Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction.Provisional matrix: A role for versican and hyaluronan.Aging fibroblasts resist phenotypic maturation because of impaired hyaluronan-dependent CD44/epidermal growth factor receptor signaling.Modulation of TGFbeta1-dependent myofibroblast differentiation by hyaluronanHyaluronan orchestrates transforming growth factor-beta1-dependent maintenance of myofibroblast phenotype.Hyaluronan induces the selective accumulation of matrix- and cell-associated proteoglycans by mesangial cells.Transforming growth factor β1 (TGFβ1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis.Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation.Hyperglycaemia and aberrated insulin signalling stimulate tumour progression via induction of the extracellular matrix component hyaluronan.
P2860
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P2860
Myofibroblastic differentiation leads to hyaluronan accumulation through reduced hyaluronan turnover.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Myofibroblastic differentiatio ...... h reduced hyaluronan turnover.
@en
type
label
Myofibroblastic differentiatio ...... h reduced hyaluronan turnover.
@en
prefLabel
Myofibroblastic differentiatio ...... h reduced hyaluronan turnover.
@en
P2093
P356
P1476
Myofibroblastic differentiatio ...... h reduced hyaluronan turnover.
@en
P2093
Gareth J Thomas
John D Williams
Robert Steadman
P304
41453-41460
P356
10.1074/JBC.M401678200
P407
P577
2004-07-22T00:00:00Z