The relationship between the metabolism of ribavirin and its proposed mechanism of action.
about
Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?RNA virus error catastrophe: direct molecular test by using ribavirinPharmacokinetics and metabolism of [14C]viramidine in rats and cynomolgus monkeysEffects of Mutagenic and Chain-Terminating Nucleotide Analogs on Enzymes Isolated from Hepatitis C Virus Strains of Various GenotypesIn vivo inhibition of respiratory syncytial virus by ribavirinT-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitroSensitive radioimmunoassay for the broad-spectrum antiviral agent ribavirinGenetic and biochemical diversity in the HCV NS5B RNA polymerase in the context of interferon α plus ribavirin therapyMetabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells.Plasma disappearance, urine excretion, and tissue distribution of ribavirin in rats and rhesus monkeysInhibition of bluetongue and Colorado tick fever orbiviruses by selected antiviral substancesChallenges for the development of ribonucleoside analogues as inducers of error catastrophe.Therapeutically targeting RNA viruses via lethal mutagenesis.Mechanism of action of ribavirin in the treatment of chronic hepatitis C.Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target.Activation and deactivation of a broad-spectrum antiviral drug by a single enzyme: adenosine deaminase catalyzes two consecutive deamination reactionsPharmacokinetics and metabolism of [(14)C]ribavirin in rats and cynomolgus monkeys.Dual-action mechanism of viramidine functioning as a prodrug and as a catabolic inhibitor for ribavirin.Reversible inhibition of cellular metabolism by ribavirin.Disposition and metabolic profiles of [14C]viramidine and [14C]ribavirin in rat and monkey red blood cells and liver.Absorption, metabolism, and excretion of [14C]viramidine in humans.Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.Antiviral activity and mode of action studies of ribavirin and mycophenolic acid against orthopoxviruses in vitro.Evidence for action of ribavirin through the hepatitis C virus RNA polymerase.Initial binding of the broad spectrum antiviral nucleoside ribavirin to the hepatitis C virus RNA polymerase.A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B.Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin.The broad spectrum antiviral nucleoside ribavirin as a substrate for a viral RNA capping enzyme.
P2860
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P2860
The relationship between the metabolism of ribavirin and its proposed mechanism of action.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
1977年论文
@zh
1977年论文
@zh-cn
name
The relationship between the m ...... proposed mechanism of action.
@en
type
label
The relationship between the m ...... proposed mechanism of action.
@en
prefLabel
The relationship between the m ...... proposed mechanism of action.
@en
P2093
P2860
P1476
The relationship between the m ...... proposed mechanism of action.
@en
P2093
P2860
P304
P356
10.1111/J.1749-6632.1977.TB21953.X
P407
P577
1977-03-01T00:00:00Z