STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.
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Sulindac induces apoptosis and inhibits tumor growth in vivo in head and neck squamous cell carcinomaSALL4, a novel marker for human gastric carcinogenesis and metastasisInterleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesisEriocalyxin B Inhibits STAT3 Signaling by Covalently Targeting STAT3 and Blocking Phosphorylation and Activation of STAT3Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cellsTherapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice.Characterization of STAT3 activation and expression in canine and human osteosarcoma.Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivors744166 polymorphism of the STAT3 gene is associated with risk of gastric cancer in a Chinese population.The reactive oxygen species-Src-Stat3 pathway provokes negative feedback inhibition of apoptosis induced by high-fluence low-power laser irradiation.Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling?The expression of antiapoptotic protein survivin is transcriptionally upregulated by DEC1 primarily through multiple sp1 binding sites in the proximal promoter.Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesisBiomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies.Genetic suppression of inflammation blocks the tumor-promoting effects of TGF-β in gastric tissue.Inhibition of STAT3 signaling prevents vascular smooth muscle cell proliferation and neointima formation.Withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells.Regulation of RKIP function by Helicobacter pylori in gastric cancer.STAT-3 correlates with lymph node metastasis and cell survival in gastric cancerDegradation of the transcription factors NF-κB, STAT3, and STAT5 is involved in Entamoeba histolytica-induced cell death in Caco-2 colonic epithelial cells.Feedback activation of STAT3 mediates trastuzumab resistance via upregulation of MUC1 and MUC4 expressionInhibition of proteasome activity by bortezomib in renal cancer cells is p53 dependent and VHL independentThe role of chalcones in suppression of NF-κB-mediated inflammation and cancer.Immunohistochemical expression of the oncogenic molecules active Stat3 and survivin in benign and malignant salivary gland tumors.(-)-Epigallocatechin-3-gallate inhibits VEGF expression induced by IL-6 via Stat3 in gastric cancer.Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models.Activation of STAT3 in human gastric cancer cells via interleukin (IL)-6-type cytokine signaling correlates with clinical implicationsSignal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivoDietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells.Possible role of REG Ialpha protein in ulcerative colitis and colitic cancerRational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells.Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro.Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α.Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signalingPrognostic significance of phosphorylated signal transducer and activator of transcription 3 and suppressor of cytokine signaling 3 expression in hepatocellular carcinoma.Effect of connective tissue growth factor on protein kinase expression and activity in human corneal fibroblastsInhibition of Jak-STAT3 pathway enhances bufalin-induced apoptosis in colon cancer SW620 cells.STAT3 is Overactivated in Gastric Cancer Stem-Like Cells
P2860
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P2860
STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
STAT3 is constitutively activa ...... ssion in gastric cancer cells.
@en
type
label
STAT3 is constitutively activa ...... ssion in gastric cancer cells.
@en
prefLabel
STAT3 is constitutively activa ...... ssion in gastric cancer cells.
@en
P2093
P2860
P356
P1433
P1476
STAT3 is constitutively activa ...... ession in gastric cancer cells
@en
P2093
Akira Sekikawa
Apichart Nanakin
Hirokazu Fukui
Hiroyuki Marusawa
Katsumasa Suzuki
Masashi Kanai
Mayumi Kawada
Mitsutaka Sawada
Naoki Kanda
Takahisa Kayahara
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207606
P407
P50
P577
2004-06-01T00:00:00Z
P5875
P6179
1012177619