Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.
about
Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibodyS100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE)Until Death Do Us Part: Necrosis and Oxidation Promote the Tumor MicroenvironmentS100A4, a mediator of metastasisA link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesisOverexpression of S100A4 in human cancer cell lines resistant to methotrexate.Signal transduction mechanisms involved in S100A4-induced activation of the transcription factor NF-kappaBS100A4 and metastasis: a small actor playing many rolesHuman mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenograftsCOX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems.Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker.Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: two ways to promote multifunctionality.S100A4 expression in xenograft tumors of human carcinoma cell lines is induced by the tumor microenvironmentS100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balanceA multiplexed, targeted mass spectrometry assay of the S100 protein family uncovers the isoform-specific expression in thyroid tumours.DAMPs, ageing, and cancer: The 'DAMP Hypothesis'.Role of Annexin-II in GI cancers: interaction with gastrins/progastrins.The metastasis associated protein S100A4: role in tumour progression and metastasisCorrelation between the expression of S100A4 and the efficacy of TAC neoadjuvant chemotherapy in breast cancer.The tumor microenvironment: key to early detection.Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology.Frequent S100A4 Expression with Unique Splicing Pattern in Gastric Cancers: A Hypomethylation Event Paralleled with E-cadherin Reduction and Wnt ActivationGenetic risk factors for portopulmonary hypertension in patients with advanced liver disease.Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytesDysregulation of matrix metalloproteinases and their tissue inhibitors by S100A4.Opposite roles of metastasin (S100A4) in two potentially tumoricidal mechanisms involving human lymphocyte protein Tag7 and Hsp70.Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth.S100 protein family in human cancer.S100A4 Elevation Empowers Expression of Metastasis Effector Molecules in Human Breast Cancer.Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression.Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53.Joining S100 proteins and migration: for better or for worse, in sickness and in health.RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis.S100A4 protects gastric cancer cells from anoikis through regulation of αv and α5 integrin.Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in miceRelaxin downregulates the calcium binding protein S100A4 in MDA-MB-231 human breast cancer cells.Calcium-binding protein S100A4 confers mesenchymal progenitor cell fibrogenicity in idiopathic pulmonary fibrosis.An efficient expression and purification strategy for the production of S100 proteins in Escherichia coli.Small interfering RNA targeting S100A4 sensitizes non-small-cell lung cancer cells (A549) to radiation treatment.
P2860
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P2860
Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.
@en
type
label
Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.
@en
prefLabel
Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.
@en
P2093
P2860
P356
P1476
Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.
@en
P2093
Annette Christensen
Birgitte Grum-Schwensen
Birgitte Schmidt-Hansen
Charlotte Kruse
Eugene Lukanidin
Jörg Klingelhöfer
Mariam Grigorian
Noona Ambartsumian
Susanne Andresen
P2860
P304
24498-24504
P356
10.1074/JBC.M400441200
P407
P577
2004-03-26T00:00:00Z