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Gene expression analysis of aberrant signaling pathways in meningiomasGlobal profiling in vestibular schwannomas shows critical deregulation of microRNAs and upregulation in those included in chromosomal region 14q32.Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR.Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.ABCG2 is required to control the sonic hedgehog pathway in side population cells with stem-like properties.Global expression profile in low grade meningiomas and schwannomas shows upregulation of PDGFD, CDH1 and SLIT2 compared to their healthy tissue.Changes in gene expression profiling of apoptotic genes in neuroblastoma cell lines upon retinoic acid treatmentFrequent promoter hypermethylation of RASSF1A and CASP8 in neuroblastomaGenome-wide microarray expression and genomic alterations by array-CGH analysis in neuroblastoma stem-like cells.Human hedgehog interacting protein expression and promoter methylation in medulloblastoma cell lines and primary tumor samplesEpigenetic regulation of human hedgehog interacting protein in glioma cell lines and primary tumor samplesThe sonic hedgehog-GLI1 signaling pathway in brain tumor development.Laminin-adherent versus suspension-non-adherent cell culture conditions for the isolation of cancer stem cells in the DAOY medulloblastoma cell line.P144, a Transforming Growth Factor beta inhibitor peptide, generates antitumoral effects and modifies SMAD7 and SKI levels in human glioblastoma cell lines.Quantitative method for in vitro matrigel invasiveness measurement through image analysis software.Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination.Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells.KIT expression and methylation in medulloblastoma and PNET cell lines and tumors.Expression and epigenetic modulation of sonic hedgehog-GLI1 pathway genes in neuroblastoma cell lines and tumors.RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs.Loss of heterozygosity and microsatellite instability on chromosome arm 10q in neuroblastoma.Potential role of Shh-Gli1-BMI1 signaling pathway nexus in glioma chemoresistance.Stromelysin-1/matrix metalloproteinase-3 (MMP-3) expression accounts for invasive properties of human astrocytoma cell lines.Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines.Whole exome sequencing in a case of sporadic multiple meningioma reveals shared NF2, FAM109B, and TPRXL mutations, together with unique SMARCB1 alterations in a subset of tumor nodules.Homozygous deletion of TNFRSF4, TP73, PPAP2B and DPYD at 1p and PDCD5 at 19q identified by multiplex ligation-dependent probe amplification (MLPA) analysis in pediatric anaplastic glioma with questionable oligodendroglial component.P-glycoprotein, HER-2/neu, and mutant p53 expression in human gynecologic tumors.Correction: Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01.On habit and the mind-body problem. The view of Felix Ravaisson.Expression analysis of tumor-related genes involved in critical regulatory pathways in schwannomas.Determination of genomic damage in neuroblastic tumors by arbitrarily primed PCR: MYCN amplification as a marker for genomic instability in neuroblastomas.Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.Molecular classification defines 4 prognostically distinct glioma groups irrespective of diagnosis and grade.Chromosomal abnormalities in human glioblastomas: gain in chromosome 7p correlating with loss in chromosome 10q.NF2 genetic alterations in sporadic vestibular schwannomas: clinical implications.Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors.c-myc oncogene amplification and cytometric DNA ploidy pattern as prognostic factors in musculoskeletal neoplasms.No association between c-myc amplification and TP53 mutation in sarcoma tumorigenesis.RASSF1A promoter is highly methylated in primitive neuroectodermal tumors of the central nervous system.DNA copy gains of tumor-related genes in vestibular schwannoma.
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P50
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hulumtues
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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J Saez-Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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Javier S. Castresana
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P106
P1153
7005901970
P21
P31
P496
0000-0002-2373-482X