Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.
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Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory element-binding protein 1cFructose, insulin resistance, and metabolic dyslipidemiaThe role of signalling in cellular cholesterol homeostasisHyperphosphorylation regulates the activity of SREBP1 during mitosis.Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity.MAPK signalling in cellular metabolism: stress or wellness?The diverse functions of oxysterol-binding proteinsAICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver.The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic CellsAdvanced Glycation End Products (AGE) Potently Induce Autophagy through Activation of RAF Protein Kinase and Nuclear Factor κB (NF-κB).Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradationTranscriptional regulation by insulin: from the receptor to the gene.Cholesterol: from feeding to gene regulation.Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cellsCasein kinase 1 regulates sterol regulatory element-binding protein (SREBP) to control sterol homeostasis.Modulation of Hepatic Protein Kinase Cβ Expression in Metabolic Adaptation to a Lithogenic DietPI3K/AKT, MAPK and AMPK signalling: protein kinases in glucose homeostasis.From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates.Novel genes in cell cycle control and lipid metabolism with dynamically regulated binding sites for sterol regulatory element-binding protein 1 and RNA polymerase II in HepG2 cells detected by chromatin immunoprecipitation with microarray detection.Mangiferin: A xanthonoid with multipotent anti-inflammatory potential.The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68.Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2.Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance.Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptakePKCβ: Expanding role in hepatic adaptation of cholesterol homeostasis to dietary fat/cholesterol.The citrus flavonoids hesperetin and nobiletin differentially regulate low density lipoprotein receptor gene transcription in HepG2 liver cells.Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis.Interaction between sterol regulatory element-binding proteins and liver receptor homolog-1 reciprocally suppresses their transcriptional activities.p38 mitogen-activated protein kinase plays an inhibitory role in hepatic lipogenesis.Phosphorylation and ubiquitination of the transcription factor sterol regulatory element-binding protein-1 in response to DNA binding.Protein phosphatase 2A (PP2A) regulates low density lipoprotein uptake through regulating sterol response element-binding protein-2 (SREBP-2) DNA binding.Role of the PI3-kinase/mTor pathway in the regulation of the stearoyl CoA desaturase (SCD1) gene expression by insulin in liver.A phosphorylation cascade controls the degradation of active SREBP1.Inhibition of cholesterol biosynthesis by 25-hydroxycholesterol is independent of OSBP.An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.Dietary flavones counteract phorbol 12-myristate 13-acetate-induced SREBP-2 processing in hepatic cells.Advanced glycation end products induce lipogenesis: regulation by natural xanthone through inhibition of ERK and NF-κB.Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes.Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats
P2860
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P2860
Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Insulin-activated Erk-mitogen- ...... residues 432 and 455 in vivo.
@en
type
label
Insulin-activated Erk-mitogen- ...... residues 432 and 455 in vivo.
@en
prefLabel
Insulin-activated Erk-mitogen- ...... residues 432 and 455 in vivo.
@en
P2093
P2860
P356
P1476
Insulin-activated Erk-mitogen- ...... e residues 432 and 455 in vivo
@en
P2093
Birgit Knebel
Dirk Muller-Wieland
Gunther Roth
Haluk Avci
Stefan Lehr
P2860
P304
22404-22411
P356
10.1074/JBC.M401198200
P407
P50
P577
2004-02-26T00:00:00Z