about
Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathwayAnti-cancer effect of thiacremonone through down regulation of peroxiredoxin 64-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity.Functional divergency oriented synthesis of azoninones as the key intermediates for bioactive indolizidine alkaloids analogs.Obovatol improves cognitive functions in animal models for Alzheimer's disease.The new 4-O-methylhonokiol analog GS12021 inhibits inflammation and macrophage chemotaxis: role of AMP-activated protein kinase α activation.Neuroprotective and antioxidant effects of novel benzofuran-2-carboxamide derivatives.Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.Nuclear factor-kappa B inhibitors; a patent review (2006-2010).Novel NF-κB inhibitors: a patent review (2011 - 2014).Anti-amyloidogenic effect of thiacremonone through anti-inflamation in vitro and in vivo models.Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis.Design and synthesis of 2,3-dihydro- and 5-chloro-2,3-dihydro-naphtho-[1,2-b]furan-2-carboxylic acid N-(substitutedphenyl)amide analogs and their biological activities as inhibitors of NF-κB activity and anticancer agents.Antioxidant and Anti-inflammatory Activities of N-((3,4-Dihydro-2H-benzo[h]chromene-2-yl)methyl)-4-methoxyaniline in LPS-Induced BV2 Microglial Cells.Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB.Design and synthesis of 3,4-dihydro-2H-benzo[h]chromene derivatives as potential NF-κB inhibitors.Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatment.Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives.Synthesis and in Vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6-diazacyclopenta[b]anthracene-5,10-diones.Synthesis and cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6,9-triazacyclopenta[b]anthracene-5,10-diones.Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect on nuclear factor-kappaB (NF-kappaB) activation.Structure-activity relationships of 6-hydroxy-7-methoxychroman-2-carboxylic acid N-(substituted)phenylamides as inhibitors of nuclear factor-kappaB activation.Synthesis and evaluation of antitumor activity of novel 1,4-naphthoquinone derivatives (IV).Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones.IRAK4 as a molecular target in the amelioration of innate immunity-related endotoxic shock and acute liver injury by chlorogenic acid.JY0691, a newly synthesized obovatol derivative, inhibits cell cycle progression of rat aortic smooth muscle cells through up-regulation of p21(cip1).Simultaneous determination of loxoprofen and its diastereomeric alcohol metabolites in human plasma and urine by a simple HPLC-UV detection method.Pharmacokinetics and metabolism of 4-O-methylhonokiol in rats.Total synthesis of anti-HIV agent chloropeptin I.Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models.Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings.Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants.Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists.Synthesis, biological evaluation, and metabolic stability of chlorogenic acid derivatives possessing thiazole as potent inhibitors of α-MSH-stimulated melanogenesis.4-O-methylhonokiol attenuated β-amyloid-induced memory impairment through reduction of oxidative damages via inactivation of p38 MAP kinase.4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease.(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol suppresses ovarian cancer cell growth via inhibition of ERK and STAT3.Synthesis of 7-hydroxy-4-oxo-4H-chromene- and 7-hydroxychroman-2-carboxylic acid N-alkyl amides and their antioxidant activities.Synthesis of 6-hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acid N-alkyl amides and their antioxidant activity.
P50
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jae-Kyung Jung
@ast
Jae-Kyung Jung
@en
Jae-Kyung Jung
@es
Jae-Kyung Jung
@sl
type
label
Jae-Kyung Jung
@ast
Jae-Kyung Jung
@en
Jae-Kyung Jung
@es
Jae-Kyung Jung
@sl
prefLabel
Jae-Kyung Jung
@ast
Jae-Kyung Jung
@en
Jae-Kyung Jung
@es
Jae-Kyung Jung
@sl
P106
P108
P1153
56587200500
7402897168
P31
P496
0000-0002-0490-9663