C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.
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1α,25(OH)2-3-epi-vitamin D3, a natural physiological metabolite of vitamin D3: its synthesis, biological activity and crystal structure with its receptorAn inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway.Metrological approaches to organic chemical purity: primary reference materials for vitamin D metabolites.Development of a candidate reference measurement procedure for the determination of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry.Development and comparison of three liquid chromatography-atmospheric pressure chemical ionization/mass spectrometry methods for determining vitamin D metabolites in human serumThe 3 epimer of 25-hydroxycholecalciferol is present in the circulation of the majority of adults in a nationally representative sample and has endogenous origins.Misleading measures in Vitamin D analysis: a novel LC-MS/MS assay to account for epimers and isobarsVitamin D metabolism, mechanism of action, and clinical applicationsThe 25-hydroxyvitamin D3 C-3 epimer: distribution, correlates, and reclassification of 25-hydroxyvitamin D status in the population-based Atherosclerosis Risk in Communities Study (ARIC)Vitamin D supplementation in breastfed infants from Montréal, Canada: 25-hydroxyvitamin D and bone health effects from a follow-up study at 3 years of age.Application of Cookson-type reagents for biomedical HPLC and LC/MS analyses: a brief overview.Vitamin D deficiency among newborns in Amman, Jordan.Discrepant association of serum C-3 epimer of 25-hydroxyvitamin D versus non-epimeric 25-hydroxyvitamin D with serum lipid levels.An assessment of 25-hydroxyvitamin D measurements in comparability studies conducted by the Vitamin D Metabolites Quality Assurance ProgramEpidemiologic study of the C-3 epimer of 25-hydroxyvitamin D(3) in a population-based sample.The Road Not So Travelled: Should Measurement of Vitamin D Epimers during Pregnancy Affect Our Clinical Decisions?Case report: Three patients with substantial serum levels of 3-epi-25(OH)D including one with 3-epi-25(OH)D2 while on high-dose ergocalciferol.The role of mass spectrometry in the analysis of vitamin D compounds.Vitamin D in chronic liver disease.Vitamin D and metabolites measurement by tandem mass spectrometry.Analysis of vitamin D metabolic markers by mass spectrometry: current techniques, limitations of the "gold standard" method, and anticipated future directions.Controversy and consensus regarding vitamin D: Recent methodological changes and the risks and benefits of vitamin D supplementation.Assessment of 3-epi-25-hydroxyvitamin D levels during cholecalciferol supplementation in adults with chronic liver diseases.The generation of C-3α epimer of 25-hydroxyvitamin D and its biological effects on bone mineral density in adult rodents.The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism.Response to "importance of C-3 epimer of 25-hydroxyvitamin D in dried blood spots of neonatal population".Previously undescribed vitamin D C-3 epimer occurs in substantial amounts in the blood of cats.Investigating Differences in Gas-Phase Conformations of 25-Hydroxyvitamin D3 Sodiated Epimers using Ion Mobility-Mass Spectrometry and Theoretical Modeling.Dietary reference values for vitamin D25-Hydroxyvitamin D3 and its C-3 epimer are elevated in the skin and serum of Skh-1 mice supplemented with dietary vitamin D3.Standardization of measurements of 25-hydroxyvitamin D3 and D2.Full-scan mass spectral evidence for 3-epi-25-hydroxyvitamin D₃ in serum of infants and adults.Maternal vitamin D biomarkers are associated with maternal and fetal bone turnover among pregnant women consuming controlled amounts of vitamin D, calcium, and phosphorus.Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ.Measurement of serum 3-epi-25-hydroxyvitamin D3, 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in infant, paediatric and adolescent populations of Korea using ultra-performance liquid chromatography-tandem mass spectrometry.Development and validation of the simultaneous measurement of four vitamin D metabolites in serum by LC-MS/MS for clinical laboratory applications.Time-course analysis of 3-epi-25-hydroxyvitamin D3 shows markedly elevated levels in early life, particularly from vitamin D supplementation in preterm infants.The When, What & How of Measuring Vitamin D Metabolism in Clinical Medicine.The genetic determinants of circulating C3-epimers of 25-hydroxyvitamin D.
P2860
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P2860
C-3 epimerization of vitamin D3 metabolites and further metabolism of C-3 epimers: 25-hydroxyvitamin D3 is metabolized to 3-epi-25-hydroxyvitamin D3 and subsequently metabolized through C-1alpha or C-24 hydroxylation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
C-3 epimerization of vitamin D ...... -1alpha or C-24 hydroxylation.
@en
type
label
C-3 epimerization of vitamin D ...... -1alpha or C-24 hydroxylation.
@en
prefLabel
C-3 epimerization of vitamin D ...... -1alpha or C-24 hydroxylation.
@en
P2093
P2860
P356
P1476
C-3 epimerization of vitamin D ...... -1alpha or C-24 hydroxylation.
@en
P2093
G Satyanarayana Reddy
Keiichi Ozono
Kuniyo Inouye
Maya Kamao
Natsumi Sawada
Noboru Kubodera
Susumi Hatakeyama
Syuichiro Tatematsu
Toshio Okano
Toshiyuki Sakaki
P2860
P304
15897-15907
P356
10.1074/JBC.M311473200
P407
P577
2004-02-02T00:00:00Z