Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region.
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Dengue: defining protective versus pathologic immunitySindbis virus interferes with dengue 4 virus replication and its potential transmission by Aedes albopictusVaccine candidates derived from a novel infectious cDNA clone of an American genotype dengue virus type 2The dengue vaccine pipeline: Implications for the future of dengue controlFunctions of the 3' and 5' genome RNA regions of members of the genus FlavivirusFever versus fever: the role of host and vector susceptibility and interspecific competition in shaping the current and future distributions of the sylvatic cycles of dengue virus and yellow fever virusViral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclizationSize heterogeneity in the 3' noncoding region of South American isolates of yellow fever virusRecombinant, live-attenuated tetravalent dengue virus vaccine formulations induce a balanced, broad, and protective neutralizing antibody response against each of the four serotypes in rhesus monkeys.Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice.West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacyPaired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes.A Live, Attenuated Dengue Virus Type 1 Vaccine Candidate with a 30-Nucleotide Deletion in the 3' Untranslated Region Is Highly Attenuated and Immunogenic in MonkeysVaccine candidates for dengue virus type 1 (DEN1) generated by replacement of the structural genes of rDEN4 and rDEN4Delta30 with those of DEN1Identification of Residues Critical for the Interferon Antagonist Function of Langat Virus NS5 Reveals a Role for the RNA-Dependent RNA Polymerase DomainAn Immunogenic and Protective Alphavirus Replicon Particle-Based Dengue Vaccine Overcomes Maternal Antibody Interference in Weanling MiceComparison of Plaque- and Flow Cytometry-Based Methods for Measuring Dengue Virus NeutralizationDengue virus type 3 vaccine candidates generated by introduction of deletions in the 3′ untranslated region (3′-UTR) or by exchange of the DENV-3 3′-UTR with that of DENV-4Asymmetric competitive suppression between strains of dengue virusSuperior infectivity for mosquito vectors contributes to competitive displacement among strains of dengue virusHigh Genetic Stability of Dengue Virus Propagated in MRC-5 Cells as Compared to the Virus Propagated in Vero CellsDengue 2 PDK-53 Virus as a Chimeric Carrier for Tetravalent Dengue Vaccine DevelopmentComparative Neuropathogenesis and Neurovirulence of Attenuated Flaviviruses in Nonhuman PrimatesEvaluation of St. Louis encephalitis virus/dengue virus type 4 antigenic chimeric viruses in mice and rhesus monkeysPhase I clinical evaluation of rDEN4Delta30-200,201: a live attenuated dengue 4 vaccine candidate designed for decreased hepatotoxicityReplication-Defective Adenoviral Vaccine Vector for the Induction of Immune Responses to Dengue Virus Type 2A recombinant West Nile virus envelope protein vaccine candidate produced in Spodoptera frugiperda expresSF+ cellsAttenuated Foot-and-Mouth Disease Virus RNA Carrying a Deletion in the 3' Noncoding Region Can Elicit Immunity in SwineDensity-Dependent Competitive Suppression of Sylvatic Dengue Virus by Endemic Dengue Virus in Cultured Mosquito CellsPassage of Dengue Virus Type 4 Vaccine Candidates in Fetal Rhesus Lung Cells Selects Heparin-Sensitive Variants That Result in Loss of Infectivity and Immunogenicity in Rhesus MacaquesPhase 1 Trial of the Dengue Virus Type 4 Vaccine Candidate rDEN4 30-4995 in Healthy Adult VolunteersMapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to DENV4 Infection and VaccinationNovel cis-acting element within the capsid-coding region enhances flavivirus viral-RNA replication by regulating genome cyclizationIn a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccinationIssues related to recent dengue vaccine development.The 5' and 3' Untranslated Regions of the Flaviviral Genome.Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus.Dengue type four viruses with E-Glu345Lys adaptive mutation from MRC-5 cells induce low viremia but elicit potent neutralizing antibodies in rhesus monkeysA human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus.Bioinformatics in new generation flavivirus vaccines.
P2860
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P2860
Attenuation and immunogenicity in humans of a live dengue virus type-4 vaccine candidate with a 30 nucleotide deletion in its 3'-untranslated region.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Attenuation and immunogenicity ...... in its 3'-untranslated region.
@en
type
label
Attenuation and immunogenicity ...... in its 3'-untranslated region.
@en
prefLabel
Attenuation and immunogenicity ...... in its 3'-untranslated region.
@en
P2093
P1476
Attenuation and immunogenicity ...... in its 3'-untranslated region
@en
P2093
A P Durbin
B R Murphy
D W Vaughn
J R Perreault
M J Reynolds
R A Karron
R M Chanock
P304
P356
10.4269/AJTMH.2001.65.405
P407
P577
2001-11-01T00:00:00Z