Mutations within lncRNAs are effectively selected against in fruitfly but not in human.
about
Volatile evolution of long noncoding RNA repertoires: mechanisms and biological implicationsRegulation of mammary epithelial cell homeostasis by lncRNAsTranscriptional regulatory functions of nuclear long noncoding RNAs.Purifying selection on splice-related motifs, not expression level nor RNA folding, explains nearly all constraint on human lincRNAs.Regulation of transcription by long noncoding RNAs.Polymorphism Analysis Reveals Reduced Negative Selection and Elevated Rate of Insertions and Deletions in Intrinsically Disordered Protein Regions.A Dual Model for Prioritizing Cancer Mutations in the Non-coding Genome Based on Germline and Somatic EventsAssessing Recent Selection and Functionality at Long Noncoding RNA Loci in the Mouse Genome.Secondary structure impacts patterns of selection in human lncRNAs.Comparative Expression Dynamics of Intergenic Long Noncoding RNAs in the Genus Drosophila.Brain-expressed 3'UTR extensions strengthen miRNA cross-talk between ion channel/transporter encoding mRNAs.Long noncoding RNAs as metazoan developmental regulators.Biological function in the twilight zone of sequence conservationEvolution to the rescue: using comparative genomics to understand long non-coding RNAs.Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii.Human long noncoding RNAs are substantially less folded than messenger RNAsUnexpected selection to retain high GC content and splicing enhancers within exons of multiexonic lncRNA loci.Conserved noncoding transcription and core promoter regulatory code in early Drosophila development.Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers.Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review
P2860
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P2860
Mutations within lncRNAs are effectively selected against in fruitfly but not in human.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Mutations within lncRNAs are effectively selected against in fruitfly but not in human.
@en
type
label
Mutations within lncRNAs are effectively selected against in fruitfly but not in human.
@en
prefLabel
Mutations within lncRNAs are effectively selected against in fruitfly but not in human.
@en
P2860
P356
P1433
P1476
Mutations within lncRNAs are effectively selected against in fruitfly but not in human.
@en
P2860
P2888
P356
10.1186/GB-2013-14-5-R49
P577
2013-05-27T00:00:00Z
P5875
P6179
1040741110