Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.
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NLRP3 Inflammasome and Pathobiology in AMDAn Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to PathologyAcid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neuronsExtracellular Acidification Acts as a Key Modulator of Neutrophil Apoptosis and FunctionsAutoimmune Disease pH and TemperatureLactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunityHexokinase II binding to mitochondria is necessary for Kupffer cell activation and is potentiated by ethanol exposureActivation and measurement of NLRP3 inflammasome activity using IL-1β in human monocyte-derived dendritic cellsAcidosis potentiates the host proinflammatory interleukin-1β response to Pseudomonas aeruginosa infectionInhibition of the NLRP3 inflammasome provides neuroprotection in rats following amygdala kindling-induced status epilepticus.Discovery of modulators of HIV-1 infection from the human peptidome.pH-Dependent recognition of apoptotic and necrotic cells by the human dendritic cell receptor DEC205.Proteolytic processing of human serum albumin generates EPI-X4, an endogenous antagonist of CXCR4.A potential role for the acid-sensing T cell death associated gene-8 (TDAG8) receptor in depression-like behavior.Gene expression markers of age-related inflammation in two human cohorts.RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, EndocineMultifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro.NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx.Proton pump inhibitors protect mice from acute systemic inflammation and induce long-term cross-tolerance.Unsolved Mysteries in NLR Biology.Acidification changes affect the inflammasome in human nucleus pulposus cells.PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.Keratin mediates the recognition of apoptotic and necrotic cells through dendritic cell receptor DEC205/CD205.Fever-range hyperthermia improves the anti-apoptotic effect induced by low pH on human neutrophils promoting a proangiogenic profile.Hiding in Plain Sight: Interplay between Staphylococcal Biofilms and Host ImmunityReal-time analysis of composite magnetic nanoparticle disassembly in vascular cells and biomimetic media.The NLRP3 inflammasome: role in airway inflammation.Danger signals in the initiation of the inflammatory response after myocardial infarction.Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors.Pattern recognition receptors and central nervous system repair.Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways.Acidification of the intimal fluid: the perfect storm for atherogenesisDanger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons.NLRP3 at the interface of metabolism and inflammation.A focus on inflammation as a major risk factor for atherosclerotic cardiovascular diseases.Phagosomal Neutralization by the Fungal Pathogen Candida albicans Induces Macrophage Pyroptosis.Effect of low extracellular pH on NF-κB activation in macrophages.Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 Cleavage.Inflammasomes link vascular disease with neuroinflammation and brain disorders.The burgeoning field of innate immune-mediated disease and autoinflammation.
P2860
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P2860
Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Extracellular acidosis is a no ...... ty via the NLRP3 inflammasome.
@en
type
label
Extracellular acidosis is a no ...... ty via the NLRP3 inflammasome.
@en
prefLabel
Extracellular acidosis is a no ...... ty via the NLRP3 inflammasome.
@en
P2093
P2860
P50
P356
P1476
Extracellular acidosis is a no ...... ity via the NLRP3 inflammasome
@en
P2093
Kari K Eklund
Karl E O Åkerman
Petri T Kovanen
P2860
P304
13410-13419
P356
10.1074/JBC.M112.426254
P407
P577
2013-03-25T00:00:00Z