Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans.
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Malate and fumarate extend lifespan in Caenorhabditis elegansThe role of INDY in metabolism, health and longevityIdentification of dicarboxylate carrier Slc25a10 as malate transporter in de novo fatty acid synthesisExpression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell linesIdentification and functional characterization of the Caenorhabditis elegans riboflavin transporters rft-1 and rft-2No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects.Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE).Structure and function of the divalent anion/Na+ symporter from Vibrio cholerae and a humanized variantCalorie restriction in mammals and simple model organisms.Increased mitochondrial biogenesis preserves intestinal stem cell homeostasis and contributes to longevity in Indy mutant flies.INDY-A New Link to Metabolic Regulation in Animals and HumansKnockout of the folate transporter folt-1 causes germline and somatic defects in C. elegans.Mitochondrial and Plasma Membrane Citrate Transporters: Discovery of Selective Inhibitors and Application to Structure/Function AnalysisThe Role of INDY in Metabolic RegulationMolecular properties of the SLC13 family of dicarboxylate and sulfate transportersThe life-extending gene Indy encodes an exchanger for Krebs-cycle intermediatesDeletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice.Distinct metabolomic signatures are associated with longevity in humans.Oat consumption reduced intestinal fat deposition and improved health span in Caenorhabditis elegans model.Knockdown of Indy/CeNac2 extends Caenorhabditis elegans life span by inducing AMPK/aak-2Ageing and metabolism: drug discovery opportunities.Dietary restriction in the nematode Caenorhabditis elegans.Knocking down transport: applications of RNA interference in the study of drug transport proteins.Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)Structure-Based Identification of Inhibitors for the SLC13 Family of Na(+)/Dicarboxylate Cotransporters.Indy mutations and Drosophila longevity.Long-lived Indy induces reduced mitochondrial reactive oxygen species production and oxidative damageLong-lived Indy and calorie restriction interact to extend life span.Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertionSodium-coupled dicarboxylate and citrate transporters from the SLC13 family.The mammalian INDY homolog is induced by CREB in a rat model of type 2 diabetes.Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc.Molecular Basis for Inhibition of the Na+/Citrate Transporter NaCT (SLC13A5) by Dicarboxylate Inhibitors.The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism.Indy mutants: live long and prosper.Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells.Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5).The longevity transporter mIndy (Slc13a5) as a target for treating hepatic steatosis and insulin resistance.A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function.Lower Doses of Fructose Extend Lifespan in Caenorhabditis elegans.
P2860
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P2860
Relevance of NAC-2, an Na+-coupled citrate transporter, to life span, body size and fat content in Caenorhabditis elegans.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Relevance of NAC-2, an Na+-cou ...... ent in Caenorhabditis elegans.
@en
type
label
Relevance of NAC-2, an Na+-cou ...... ent in Caenorhabditis elegans.
@en
prefLabel
Relevance of NAC-2, an Na+-cou ...... ent in Caenorhabditis elegans.
@en
P2093
P2860
P356
P1433
P1476
Relevance of NAC-2, an Na+-cou ...... ent in Caenorhabditis elegans.
@en
P2093
Jin-Cai Liu
Katsuhisa Inoue
Katsuya Miyake
Lina Zhuang
Seiji Miyauchi
You-Jun Fei
P2860
P304
P356
10.1042/BJ20031807
P407
P577
2004-04-01T00:00:00Z