Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability. - Wikidata - wikimedia - TriplyDB

Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.

Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.

http://www.wikidata.org/entity/Q40625455

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The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana.Neurological disorders associated with DNA strand-break processing enzymes.DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.Coordination of DNA single strand break repair.The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair.Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease Characterization of DNA Substrate Binding to the Phosphatase Domain of the DNA Repair Enzyme Polynucleotide Kinase/Phosphatase Lingering single-strand breaks trigger Rad51-independent homology-directed repair of collapsed replication forks in the polynucleotide kinase/phosphatase mutant of fission yeast.Genome integrity and disease prevention in the nervous system.Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery.

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Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.

http://www.wikidata.org/entity/Q40625455

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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name

Polynucleotide kinase-phosphat ...... to maintain genome stability.

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type

label

Polynucleotide kinase-phosphat ...... to maintain genome stability.

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prefLabel

Polynucleotide kinase-phosphat ...... to maintain genome stability.

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The EMBO Journal

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Polynucleotide kinase-phosphat ...... to maintain genome stability.

@en

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Helen R Russell

http://www.w3.org/2001/XMLSchema#string

Lavinia C Dumitrache

http://www.w3.org/2001/XMLSchema#string

Mikio Shimada

http://www.w3.org/2001/XMLSchema#string

Peter J McKinnon

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3'-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage

The role of double-strand break repair — insights from human genetics

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair

Functional role for senataxin, defective in ataxia oculomotor apraxia type 2, in transcriptional regulation

A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors

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2465-2480

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scholarly article

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10.15252/EMBJ.201591363

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19

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34

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2015-08-19T00:00:00Z

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26290337

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4601665

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