ADF/cofilin binds phosphoinositides in a multivalent manner to act as a PIP(2)-density sensor.
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Phosphoinositides: tiny lipids with giant impact on cell regulationMinimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1Solution structure and dynamics of ADF from Toxoplasma gondiiCofilin-1 and Other ADF/Cofilin Superfamily Members in Human Malignant Cellsdusky-like is required to maintain the integrity and planar cell polarity of hairs during the development of the Drosophila wing.Considering protonation as a posttranslational modification regulating protein structure and function.The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.Roles of ADF/cofilin in actin polymerization and beyondA conserved regulatory mode in exocytic membrane fusion revealed by Mso1p membrane interactions.Actin-interacting Protein 1 Promotes Disassembly of Actin-depolymerizing Factor/Cofilin-bound Actin Filaments in a pH-dependent Manner.Phosphoinositides and membrane curvature switch the mode of actin polymerization via selective recruitment of toca-1 and Snx9Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM KinasesDensity-dependent cooperative non-specific binding in solid-phase SELEX affinity selection.Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative diseaseCompetitive displacement of cofilin can promote actin filament severingA reducing milieu renders cofilin insensitive to phosphatidylinositol 4,5-bisphosphate (PIP2) inhibition.Actin-depolymerizing factor homology domain: a conserved fold performing diverse roles in cytoskeletal dynamics.A simple guide to biochemical approaches for analyzing protein-lipid interactions.Functions of cofilin in cell locomotion and invasion.PIP2: choreographer of actin-adaptor proteins in the HIV-1 dance.Differential SKIP expression in PTEN-deficient glioblastoma regulates cellular proliferation and migration.Plant actin depolymerizing factor: actin microfilament disassembly and more.Quantitative Evaluation of Viral Protein Binding to Phosphoinositide Receptors and Pharmacological Inhibition.Membrane-sculpting BAR domains generate stable lipid microdomains.Identification of new surfaces of cofilin that link mitochondrial function to the control of multi-drug resistance.Phosphoinositide Binding Inhibits Actin Crosslinking and Polymerization by Palladin.The initiation of post-synaptic protrusions.Phosphosite conservation in single domain orthologs versus paralogs: a way to combine differential regulation with redundant core functions.Mechanistic principles underlying regulation of the actin cytoskeleton by phosphoinositides.Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2.Molecular mechanism for inhibition of twinfilin by phosphoinositides.Fluconazole-induced actin cytoskeleton remodeling requires phosphatidylinositol 3-phosphate 5-kinase in the pathogenic yeast Candida glabrata
P2860
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P2860
ADF/cofilin binds phosphoinositides in a multivalent manner to act as a PIP(2)-density sensor.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
ADF/cofilin binds phosphoinosi ...... ct as a PIP(2)-density sensor.
@en
type
label
ADF/cofilin binds phosphoinosi ...... ct as a PIP(2)-density sensor.
@en
prefLabel
ADF/cofilin binds phosphoinosi ...... ct as a PIP(2)-density sensor.
@en
P2860
P1433
P1476
ADF/cofilin binds phosphoinosi ...... act as a PIP(2)-density sensor
@en
P2093
Hongxia Zhao
Pekka Lappalainen
P2860
P304
P356
10.1016/J.BPJ.2010.01.046
P407
P577
2010-05-01T00:00:00Z