Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury.
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Nitric oxide and peroxynitrite in health and diseaseAntioxidant responses and cellular adjustments to oxidative stressMitochondrial dysfunction and tissue injury by alcohol, high fat, nonalcoholic substances and pathological conditions through post-translational protein modificationsEndothelial dysfunction in cirrhosis: Role of inflammation and oxidative stressMitochondrial glutathione: features, regulation and role in diseaseChronic alcohol consumption potentiates the development of diabetes through pancreatic β-cell dysfunctionNitric oxide synthases: regulation and functionCharacterization of potential S-nitrosylation sites in the myocardiumFo Shou San, an ancient Chinese herbal decoction, protects endothelial function through increasing endothelial nitric oxide synthase activityA proteomic analysis of liver after ethanol binge in chronically ethanol treated ratsS-Nitrosylation of p47(phox) enhances phosphorylation by casein kinase 2.Membrane proteome analysis of cerulein-stimulated pancreatic acinar cells: implication for early event of acute pancreatitis.Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells.Chemical model systems for cellular nitros(yl)ation reactions.Nitric Oxide and Related Aspects Underlying Angina.Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolismMechanism of gallic acid biosynthesis in bacteria (Escherichia coli) and walnut (Juglans regia)The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens.Chronic ethanol consumption-induced pancreatic {beta}-cell dysfunction and apoptosis through glucokinase nitration and its down-regulation.Role of Mitochondria in Alcoholic Liver DiseaseΚ-opioid receptor stimulation improves endothelial function in hypoxic pulmonary hypertension.Aniline-induced nitrosative stress in rat spleen: proteomic identification of nitrated proteins.Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes.The volatile oil of Nardostachyos Radix et Rhizoma induces endothelial nitric oxide synthase activity in HUVEC cells.SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status.Mitochondrial glutathione and chemically induced stress including ethanol.Oxidative stress evokes a metabolic adaptation that favors increased NADPH synthesis and decreased NADH production in Pseudomonas fluorescensMitochondria as a target for early detection and diagnosis of cancer.Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases.Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis.Ethanol metabolism and effects: nitric oxide and its interaction.Vascular aging: chronic oxidative stress and impairment of redox signaling-consequences for vascular homeostasis and disease.Nitrosative stress and redox-cycling agents synergize to cause mitochondrial dysfunction and cell death in endothelial cells.Modulation of lysozyme function and degradation after nitration with peroxynitrite.Mitochondria and energetic depression in cell pathophysiologyImpaired TCA cycle flux in mitochondria in skeletal muscle from type 2 diabetic subjects: marker or maker of the diabetic phenotype?IDH2 knockdown sensitizes tumor cells to emodin cytotoxicity in vitro and in vivo.Glutathionylation regulates cytosolic NADP+-dependent isocitrate dehydrogenase activity.An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation.
P2860
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P2860
Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Inactivation of NADP+-dependen ...... alcohol-induced liver injury.
@en
type
label
Inactivation of NADP+-dependen ...... alcohol-induced liver injury.
@en
prefLabel
Inactivation of NADP+-dependen ...... alcohol-induced liver injury.
@en
P2093
P2860
P356
P1476
Inactivation of NADP+-dependen ...... alcohol-induced liver injury.
@en
P2093
Eun Sun Yang
Jeen-Woo Park
Jin Hyup Lee
P2860
P304
51360-51371
P356
10.1074/JBC.M302332200
P407
P577
2003-10-09T00:00:00Z