Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

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http://www.wikidata.org/entity/Q40629513

Q40629513

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Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.A house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell death Pathways involved in testicular germ cell apoptosis induced by H2O2 in vitro β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells.Anti-angiogenic effect of tetraacetyl-phytosphingosine.Pharmacological inhibition of sphingosine kinase isoforms alters estrogen receptor signaling in human breast cancer.Endoplasmic reticulum stress-induced JNK activation is a critical event leading to mitochondria-mediated cell death caused by β-lapachone treatment.Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway.Ethanol Mediates Cell Cycle Arrest and Apoptosis in SK-N-SH Neuroblastoma Cells.The anti-tumour compound, RH1, causes mitochondria-mediated apoptosis by activating c-Jun N-terminal kinase.Methyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells p38 MAPK as a negative regulator of VEGF/VEGFR2 signaling pathway in serum deprived human SK-N-SH neuroblastoma cells.Study of the Effects of Betaine and/or C-Phycocyanin on the Growth of Lung Cancer A549 Cells In Vitro and In Vivo Androgen receptor (AR) positive vs negative roles in prostate cancer cell deaths including apoptosis, anoikis, entosis, necrosis and autophagic cell death.Mitochondrial regulation of cell cycle and proliferation.Cytotoxic effects of novel phytosphingosine derivatives, including N,N-dimethylphytosphingosine and N-monomethylphytosphingosine, in human leukemia cell line HL60.Inhibitory effects of N,N,N-trimethyl phytosphingosine-iodide on melanogenesis via ERK activation-mediated MITF degradation.Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways.Targeting RET to induce medullary thyroid cancer cell apoptosis: an antagonistic interplay between PI3K/Akt and p38MAPK/caspase-8 pathways.Citrus limonin lacks the antichemotherapeutic effect in human models of breast cancer.Pachastrissamine from Pachastrissa sp. inhibits melanoma cell growth by dual inhibition of Cdk2 and ERK-mediated FOXO3 downregulation.Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives.Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate P2Y2 nucleotide receptors inhibit trauma-induced death of astrocytic cells.p38 MAPK and MSK1 mediate caspase-8 activation in manganese-induced mitochondria-dependent cell death.Inactivation of CaMIT1 inhibits Candida albicans phospholipomannan beta-mannosylation, reduces virulence, and alters cell wall protein beta-mannosylation.Delayed Cell Cycle Progression and Apoptosis Induced by Hemicellulase-Treated Agaricus blazei.G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase.Phytosphingosine induced mitochondria-involved apoptosis.Microarray analysis reveals pivotal divergent mRNA expression profiles early in the development of either compensated ventricular hypertrophy or heart failure.HSP25 inhibits radiation-induced apoptosis through reduction of PKCdelta-mediated ROS production.Phorbol myristate acetate induces neutrophil death through activation of p38 mitogen-activated protein kinase that requires endogenous reactive oxygen species other than HOCl.TGFbeta-mediated apoptosis of Burkitt's lymphoma BL41 cells is associated with the relocation of mitochondrial BimEL.Activator protein-1 in human male germ cell apoptosis.p38-NF-κB-promoted mitochondria-associated apoptosis and G2/M cell cycle arrest in norcantharidin-treated HeLa cells.Dihydroartemisinin sensitizes Lewis lung carcinoma cells to carboplatin therapy via p38 mitogen-activated protein kinase activation.PPARβ/δ Agonist GW501516 Inhibits Tumorigenicity of Undifferentiated Nasopharyngeal Carcinoma in C666-1 Cells by Promoting Apoptosis.

P2860

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P2860

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

Item

http://www.wikidata.org/entity/Q40629513

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Suppression of extracellular s ...... ne-treated human cancer cells.

@en

type

Item

label

Suppression of extracellular s ...... ne-treated human cancer cells.

@en

prefLabel

Suppression of extracellular s ...... ne-treated human cancer cells.

@en

P1476

Suppression of extracellular s ...... ne-treated human cancer cells.

@en

P2093

Chang-Mo Kang

http://www.w3.org/2001/XMLSchema#string

Chul-Koo Cho

http://www.w3.org/2001/XMLSchema#string

Hong-Duck Um

http://www.w3.org/2001/XMLSchema#string

Jung-A Choi

http://www.w3.org/2001/XMLSchema#string

Min-Jeong Kim

http://www.w3.org/2001/XMLSchema#string

Moon-Taek Park

http://www.w3.org/2001/XMLSchema#string

Sangwoo Bae

http://www.w3.org/2001/XMLSchema#string

Seongman Kang

http://www.w3.org/2001/XMLSchema#string

Su-Jae Lee

http://www.w3.org/2001/XMLSchema#string

Yun-Sil Lee

http://www.w3.org/2001/XMLSchema#string

P2860

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy

Signal transduction by the JNK group of MAP kinases

Mammalian MAP kinase signalling cascades

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation

Heat-shock protein 70 antagonizes apoptosis-inducing factor

Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8

Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils

Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells

P304

50624-50634

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P31

scholarly article

P356

10.1074/JBC.M309011200

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

278

http://www.w3.org/2001/XMLSchema#string

P50

Hee Yong Chung

P577

2003-09-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

14522966

http://www.w3.org/2001/XMLSchema#string

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

about

P2860

P2860

Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.

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P1433

P1476

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P2860

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P356

P407

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P478

P50

P577

P698

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P1433

P1476

P2093

P2860

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P31

P356

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P433

P478

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P698