Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.

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The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase.

P2860

Q42766013-FC3D5C0D-76BF-4A20-99D7-FACA7C27698F

P2860

Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.

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http://www.wikidata.org/entity/Q40629852

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2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

Synthesis, solution conformati ...... eir 4,5-substituted analogues.

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Synthesis, solution conformati ...... eir 4,5-substituted analogues.

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Synthesis, solution conformati ...... eir 4,5-substituted analogues.

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P1476

Synthesis, solution conformati ...... eir 4,5-substituted analogues.

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Tadeusz Kulikowski

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P2860

Comparisons of anti-human immunodeficiency virus activities, cellular transport, and plasma and intracellular pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine

An analysis of the inhibition of replication of HIV and MuLV by some 3'-blocked pyrimidine analogs

HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy

Nature, time course and dose dependence of zidovudine-related side effects: results from the Multicenter Canadian Azidothymidine Trial

The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus.

Nucleoside conformation is determined by the electronegativity of the sugar substituent.

3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues.

Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.

Anemia and erythropoiesis in patients with the acquired immunodeficiency syndrome (AIDS) and Kaposi sarcoma treated with zidovudine.

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127-138

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scholarly article

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10.1177/095632020301400302

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276482180

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14521329

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Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.

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P2860

P2860

Synthesis, solution conformation and anti-HIV activity of novel 3'-substituted-2',3'-dideoxy-5-hydroxymethyluridines and their 4,5-substituted analogues.

description

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P1433

P1476

P2093

P2860

P304

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P356

P433

P478

P50

P577

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P698

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P1433

P1476

P2093

P2860

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P31

P356

P433

P478

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P5875

P698