Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.
about
Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression dataAutomated measurement of cell motility and proliferation.Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discoveryPharmGKB summary: very important pharmacogene information for N-acetyltransferase 2RNAi-mediated knock-down of arylamine N-acetyltransferase-1 expression induces E-cadherin up-regulation and cell-cell contact growth inhibitionA novel color change mechanism for breast cancer biomarker detection: naphthoquinones as specific ligands of human arylamine N-acetyltransferase 1From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2Comparative proteome analysis of breast cancer and adjacent normal breast tissues in human.Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues.Inflammatory cytokines suppress arylamine N-acetyltransferase 1 in cholangiocarcinoma cellsGenetic polymorphisms in the metabolic pathway and non-Hodgkin lymphoma survivalEffects of human arylamine N-acetyltransferase I knockdown in triple-negative breast cancer cell lines.NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenylPhenotype of the most common "slow acetylator" arylamine N-acetyltransferase 1 genetic variant (NAT1*14B) is substrate-dependent.Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice.Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1Folate-Dependent Hydrolysis of Acetyl-Coenzyme A by Recombinant Human and Rodent Arylamine N-Acetyltransferases.Glucocorticoid receptor-mediated transcriptional regulation of N-acetyltransferase 1 gene through distal promoterFunctional analysis of the human N-acetyltransferase 1 major promoter: quantitation of tissue expression and identification of critical sequence elements.Congenic rats with higher arylamine N-acetyltransferase 2 activity exhibit greater carcinogen-induced mammary tumor susceptibility independent of carcinogen metabolism.Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker.Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism.Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system.A novel gene expression signature for bone metastasis in breast carcinomas.Untargeted polar metabolomics of transformed MDA-MB-231 breast cancer cells expressing varying levels of human arylamine N-acetyltransferase 1.Arylamine N-acetyltransferases: a structural perspective.Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.High N-acetyltransferase 1 (NAT1) expression is associated with estrogen receptor expression in breast tumors, but is not under direct regulation by estradiol, 17beta-diol, or dihydrotestosterone in breast cancer cells.Genetic and small molecule inhibition of arylamine N-acetyltransferase 1 reduces anchorage-independent growth in human breast cancer cell line MDA-MB-231.Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability.Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance.
P2860
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P2860
Arylamine N-acetyltransferase-1 is highly expressed in breast cancers and conveys enhanced growth and resistance to etoposide in vitro.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Arylamine N-acetyltransferase- ...... istance to etoposide in vitro.
@en
type
label
Arylamine N-acetyltransferase- ...... istance to etoposide in vitro.
@en
prefLabel
Arylamine N-acetyltransferase- ...... istance to etoposide in vitro.
@en
P2093
P1476
Arylamine N-acetyltransferase- ...... sistance to etoposide in vitro
@en
P2093
Adrian L Harris
Alasdair C Stamps
Francesco Pezzella
Graham Craggs
Graham Steers
Jackie De Belin
Joanne Berry
Jonathan A Terrett
Julie A Loader
Kerry L Tyson
P304
P577
2003-09-01T00:00:00Z