Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation.
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Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistanceEvaluating Inhibition of the Epidermal Growth Factor (EGF)-Induced Response of Mutant MCF10A Cells with an Acoustic Sensor.Multiple model-informed open-loop control of uncertain intracellular signaling dynamicsSmall-molecule inhibitors of signal transduction pathways in leukemia therapeutics: how to assess selectivity for malignant signals.JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis.Raf and VEGF: emerging therapeutic targets in Kaposi's sarcoma-associated herpesvirus infection and angiogenesis in hematopoietic and nonhematopoietic tumors.The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway andBicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways.The function and dynamics of the apical scaffolding protein E3KARP are regulated by cell-cycle phosphorylation.The epidermal growth factor receptor gene family as a target for therapeutic intervention in numerous cancers: what's genetics got to do with it?MR-1 blocks the megakaryocytic differentiation and transition of CML from chronic phase to blast crisis through MEK dephosphorylation.Targeting the PI3K and MAPK pathways to treat Kaposi's-sarcoma-associated herpes virus infection and pathogenesis.Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.Deguelin Induces the Apoptosis of Lung Squamous Cell Carcinoma Cells through Regulating the Expression of Galectin-1.Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.Emerging Raf inhibitors.Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.New therapeutic approaches to acute myeloid leukemia.MAP kinases and the inflammatory signaling cascade as targets for the treatment of endometriosis?Inhibition of PI3K, mTOR and MEK signaling pathways promotes rapid apoptosis in B-lineage ALL in the presence of stromal cell support.Raf promotes human herpesvirus-8 (HHV-8/KSHV) infection.New perspectives for targeting RAF kinase in human cancer.The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis.Development of small-molecule therapeutics and strategies for targeting RAF kinase in BRAF-mutant colorectal cancer
P2860
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P2860
Differential effects of kinase cascade inhibitors on neoplastic and cytokine-mediated cell proliferation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Differential effects of kinase ...... e-mediated cell proliferation.
@en
type
label
Differential effects of kinase ...... e-mediated cell proliferation.
@en
prefLabel
Differential effects of kinase ...... e-mediated cell proliferation.
@en
P2093
P2860
P356
P1433
P1476
Differential effects of kinase ...... e-mediated cell proliferation.
@en
P2093
Blalock WL
Franklin RA
McCubrey JA
Shelton JG
Steelman LS
P2860
P2888
P304
P356
10.1038/SJ.LEU.2403052
P577
2003-09-01T00:00:00Z
P5875
P6179
1010826794