Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits.
about
Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1Structural plasticity and conformational transitions of HIV envelope glycoprotein gp120Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobilityFunctional stability of unliganded envelope glycoprotein spikes among isolates of human immunodeficiency virus type 1 (HIV-1)Oligomer-specific conformations of the human immunodeficiency virus (HIV-1) gp41 envelope glycoprotein ectodomain recognized by human monoclonal antibodiesStoichiometry of envelope glycoprotein trimers in the entry of human immunodeficiency virus type 1A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer.Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions.Epitope target structures of Fc-mediated effector function during HIV-1 acquisition.Single-particle cryoelectron microscopy analysis reveals the HIV-1 spike as a tripod structure.An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes.Structure and immune recognition of trimeric pre-fusion HIV-1 Env.Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer.High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection.Lineage-specific differences between human and simian immunodeficiency virus regulation of gp120 trimer association and CD4 bindingAdaptation of the human immunodeficiency virus type 1 envelope glycoproteins to new world monkey receptors.Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated CytotoxicityThe highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.Forced virus evolution reveals functional crosstalk between the disulfide bonded region and membrane proximal ectodomain region of HIV-1 gp41A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization.Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domainRole of hydrophobic residues in the central ectodomain of gp41 in maintaining the association between human immunodeficiency virus type 1 envelope glycoprotein subunits gp120 and gp41.Characterization of the outer domain of the gp120 glycoprotein from human immunodeficiency virus type 1Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity.Histidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins.Lineage-Specific Differences between the gp120 Inner Domain Layer 3 of Human Immunodeficiency Virus and That of Simian Immunodeficiency VirusEffects of sequence changes in the HIV-1 gp41 fusion peptide on CCR5 inhibitor resistance.HIV-1 Escape from a Peptidic Anchor Inhibitor through Stabilization of the Envelope Glycoprotein SpikeRole of complex carbohydrates in human immunodeficiency virus type 1 infection and resistance to antibody neutralizationInfluence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors.A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability.Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.An unrelated monoclonal antibody neutralizes human immunodeficiency virus type 1 by binding to an artificial epitope engineered in a functionally neutral region of the viral envelope glycoproteins.Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses.
P2860
Q26782237-2DB4E911-8777-42AC-9B59-AB3942A49263Q27327645-21FBDFC0-1AD4-4695-9931-22546345F493Q27658989-A5A2582B-BCCC-4C74-A943-E85E5C1881BDQ28743199-0622FD27-3EA1-4948-8DBB-25318114A917Q30436401-208DBF73-D9D2-4795-B10D-CD97E814B298Q30447936-F420A45A-F0C5-473C-832E-780F054FE421Q33725702-1E57D0B2-EA9A-47A1-BE94-86E9FC15A784Q33789251-5B91BB03-2AF5-4C8E-A853-AB98A7D6A9B6Q33924272-8A1B55A3-F308-4384-AFB5-DDE26BA0BE4DQ34279140-B9CF512A-A31D-4DBC-9203-C2BFE51ED457Q34987062-233BF523-14C6-481F-9A40-6663CDBDF8BEQ35142291-82D6F9A1-9CE1-4C7D-B14B-20A0886FB5F7Q35596474-37894DED-5138-44EF-BB8E-AD891A8FF83EQ35826509-79A3EAF1-430E-46FF-8CC7-69FB2CAEC0F3Q36155019-F085F57C-C5CD-4DC3-A5BA-73EE2E801ED6Q36423960-AF94F61B-8302-41EA-A034-A3E43C18B9EBQ36538762-BFDF0D13-A198-4661-97E0-3BF42A4317CCQ36607016-CF82BA16-E84C-478B-B669-BE40C8FD502EQ36814871-8A74E544-0834-40DC-B7ED-2DF360D63476Q36827883-2F8C6DBA-E7FB-441E-B169-583FBD9E0017Q36978861-C56B12A5-8549-4558-8875-BA7C669D773DQ37333789-EEFD4704-7D56-44A1-9FF0-8F2A4C1C879CQ37422890-1A86FD6F-DC5A-4396-9D59-A765D657586CQ37596552-2CBB0024-55D4-47E8-A84E-2B2A36F5E920Q37644079-EF9BB1F9-3508-4ADF-AC7A-FE708B778024Q38727214-ED1577EE-3635-4D5F-9CA5-39A12023CC7FQ38736210-33CCC0CD-14F0-490A-9C40-FAE81403D365Q39361526-BAC26292-4739-4FB4-B1CC-AB79F3C52E25Q39365785-B21D21A2-8D8B-4E73-B31A-F1E5EA3ACB89Q39723388-30F44429-64D4-42EB-BA9A-0677FBDFAB6DQ40366464-F9421CEA-B392-47DE-A958-E8E923912998Q40399853-120A667B-C1CE-4DB9-B919-431DF73B86F2Q40664564-ABDD09DB-E930-4E98-B5B0-3899D8A2D903Q40730039-7CAF1488-85D0-4981-AEBC-79F20E0B3D54Q42086489-65ECBDD3-C034-495C-AE52-FA8051B67B8EQ55411165-7EF35E6A-28A4-421F-B8B0-80A6FF6190F9
P2860
Role of the gp120 inner domain beta-sandwich in the interaction between the human immunodeficiency virus envelope glycoprotein subunits.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Role of the gp120 inner domain ...... nvelope glycoprotein subunits.
@en
type
label
Role of the gp120 inner domain ...... nvelope glycoprotein subunits.
@en
prefLabel
Role of the gp120 inner domain ...... nvelope glycoprotein subunits.
@en
P2093
P1433
P1476
Role of the gp120 inner domain ...... nvelope glycoprotein subunits.
@en
P2093
Aemro Kassa
Erin Mahony
Geoff H Holm
Xinzhen Yang
P304
P356
10.1016/S0042-6822(03)00273-3
P407
P577
2003-08-01T00:00:00Z