Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro.
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A new yeast poly(A) polymerase complex involved in RNA quality controlInositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylationMultiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processingMultiple forms of poly(A) polymerases in human cellsInfluenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery.Cleavage and polyadenylation factor CPF specifically interacts with the pre-mRNA 3' processing signal AAUAAAAssembly of a processive messenger RNA polyadenylation complexCharacterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunitX-ray Crystallographic and Steady State Fluorescence Characterization of the Protein Dynamics of Yeast Polyadenylate PolymeraseFormation of the 3' end of histone mRNA: getting closer to the endA multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substratesControl of poly(A) polymerase level is essential to cytoplasmic polyadenylation and early development in DrosophilaIsolation and characterization of polyadenylation complexes assembled in vitro.Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33.Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism.Alternative poly(A) site selection in complex transcription units: means to an end?Inhibition of cdk9 during herpes simplex virus 1 infection impedes viral transcriptionAra-ATP impairs 3'-end processing of pre-mRNAs by inhibiting both cleavage and polyadenylation.The end of the message: 3'-end processing leading to polyadenylated messenger RNA.Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner.Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms.RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor.PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I.Mitochondrial poly(A) polymerase is involved in tRNA repair.Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.Polyadenylation-specific complexes undergo a transition early in the polymerization of a poly(A) tailThe enzyme that adds poly(A) to mRNAs is a classical poly(A) polymerase.Polyadenylation of mRNA: minimal substrates and a requirement for the 2' hydroxyl of the U in AAUAAA.Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3'-end formation.Sequences upstream of AAUAAA influence poly(A) site selection in a complex transcription unit.Conditional defect in mRNA 3' end processing caused by a mutation in the gene for poly(A) polymeraseAn investigation into the role of ATP in the mammalian pre-mRNA 3' cleavage reactionPoly(A) polymerase contains multiple functional domains.Assembly of the cleavage and polyadenylation apparatus requires about 10 seconds in vivo and is faster for strong than for weak poly(A) sitesOptimizing In Vitro Pre-mRNA 3' Cleavage Efficiency: Reconstitution from Anion-Exchange Separated HeLa Cleavage Factors and from Adherent HeLa Cell Nuclear Extract.Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA.Identification of an activity in B-cell extracts that selectively impairs the formation of an immunoglobulin mu s poly(A) site processing complex.Termination of transcription in an 'in vitro' system is dependent on a polyadenylation sequence.Regulation of polyadenylation in hepatitis B viruses: stimulation by the upstream activating signal PS1 is orientation-dependent, distance-independent, and additive.Potential role of poly(A) polymerase in the assembly of polyadenylation-specific RNP complexes.
P2860
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P2860
Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Poly(A) polymerase purified fr ...... nylation of pre-mRNA in vitro.
@en
type
label
Poly(A) polymerase purified fr ...... nylation of pre-mRNA in vitro.
@en
prefLabel
Poly(A) polymerase purified fr ...... nylation of pre-mRNA in vitro.
@en
P2860
P356
P1476
Poly(A) polymerase purified fr ...... nylation of pre-mRNA in vitro.
@en
P2093
Christofori G
P2860
P304
P356
10.1128/MCB.9.1.193
P407
P577
1989-01-01T00:00:00Z