The chemotherapeutic agent bortezomib induces the formation of stress granules.
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Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?Advances in the understanding of mechanisms and therapeutic use of bortezomibRole of HRI in apoptosis resistanceYB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1.Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes.p21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis.Analysis of translation initiation during stress conditions by polysome profiling.Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system.Stress granules, P-bodies and cancer.New PARP targets for cancer therapySensitizing human multiple myeloma cells to the proteasome inhibitor bortezomib by novel curcumin analogs.mRNP granules. Assembly, function, and connections with disease.Selenite targets eIF4E-binding protein-1 to inhibit translation initiation and induce the assembly of non-canonical stress granules.Lysine acetyltransferase NuA4 and acetyl-CoA regulate glucose-deprived stress granule formation in Saccharomyces cerevisiae.Can we observe changes in mRNA "state"? Overview of methods to study mRNA interactions with regulatory proteins relevant in cancer related processes.From bortezomib to other inhibitors of the proteasome and beyond.ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases.Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation.Sensitization of U937 leukemia cells to doxorubicin by the MG132 proteasome inhibitor induces an increase in apoptosis by suppressing NF-kappa B and mitochondrial membrane potential loss.The biological and therapeutic relevance of mRNA translation in cancer.Nucleoli and stress granules: connecting distant relatives.Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.mRNPs meet stress granules.Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.Sorafenib, a multikinase inhibitor, induces formation of stress granules in hepatocarcinoma cells.Stress granules at the intersection of autophagy and ALS.5-Fluorouracil affects assembly of stress granules based on RNA incorporation.Quantitative proteomic analysis to decipher the differential apoptotic response of bortezomib-treated APL cells before and after retinoic acid differentiation reveals involvement of protein toxicity mechanisms.Inactivation of the mTORC1-eukaryotic translation initiation factor 4E pathway alters stress granule formation.RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLDAggregation of SND1 in Stress Granules is Associated with the Microtubule Cytoskeleton During Heat Shock Stimulus.Disease of mRNA Regulation: Relevance for Ischemic Brain Injury.Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules.AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule OrganizationHRI-mediated translational repression reduces proteotoxicity and sensitivity to bortezomib in human pancreatic cancer cells.Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability
P2860
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P2860
The chemotherapeutic agent bortezomib induces the formation of stress granules.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The chemotherapeutic agent bortezomib induces the formation of stress granules.
@en
type
label
The chemotherapeutic agent bortezomib induces the formation of stress granules.
@en
prefLabel
The chemotherapeutic agent bortezomib induces the formation of stress granules.
@en
P2093
P2860
P356
P1476
The chemotherapeutic agent bortezomib induces the formation of stress granules.
@en
P2093
Cristina Gareau
Marie-Josée Fournier
Rachid Mazroui
P2860
P2888
P356
10.1186/1475-2867-10-12
P577
2010-04-29T00:00:00Z
P5875
P6179
1043972931