Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells. - Wikidata - wikimedia - TriplyDB

Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells.

Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells.

http://www.wikidata.org/entity/Q40651643

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Suppressor of cytokine signaling-3 antagonizes cAMP effects on proliferation and apoptosis and is expressed in human prostate cancer Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer Nucleic acid-based approaches to STAT inhibition Signal transducer and activator of transcription 5A/B in prostate and breast cancers Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland S731 in the transactivation domain modulates STAT5b activity.The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways.STAT5 regulation of BCL10 parallels constitutive NFkappaB activation in lymphoid tumor cells.Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth.DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells IL-15 prolongs CD154 expression on human CD4 T cells via STAT5 binding to the CD154 transcriptional promoter.Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer.Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer.FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.Roles and regulation of stat family transcription factors in human breast cancer.Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase signaling cascades.The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activity Nanoparticle delivery of a peptide targeting EGFR signaling Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.Signal transducer and activator of transcription-5 mediates neuronal apoptosis induced by inhibition of Rac GTPase activity.Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.STAT5b as molecular target in pancreatic cancer--inhibition of tumor growth, angiogenesis, and metastases.Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians.STAT5A/B gene locus undergoes amplification during human prostate cancer progression.Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion.Androgen-regulated and highly tumorigenic human prostate cancer cell line established from a transplantable primary CWR22 tumor.Transcription factors: their potential as targets for an individualized therapeutic approach to cancer.Androgen receptor-dependent and -independent mechanisms driving prostate cancer progression: Opportunities for therapeutic targeting from multiple angles.Targeting transcription factor Stat5a/b as a therapeutic strategy for prostate cancer.Prolactin regulation of the prostate gland: a female player in a male game.The role of transcription factors in prostate cancer and potential for future RNA interference therapy.Robust gene network analysis reveals alteration of the STAT5a network as a hallmark of prostate cancer.Prolactin- and testosterone-induced carboxypeptidase-D correlates with increased nitrotyrosines and Ki67 in prostate cancer.Estimation of High-Dimensional Graphical Models Using Regularized Score Matching.Growth hormone enhances LNCaP prostate cancer cell motility.Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting.

P2860

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P2860

Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells.

http://www.wikidata.org/entity/Q40651643

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

Inhibition of transcription fa ...... f human prostate cancer cells.

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Inhibition of transcription fa ...... f human prostate cancer cells.

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Inhibition of transcription fa ...... f human prostate cancer cells.

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Journal of Biological Chemistry

P1476

Inhibition of transcription fa ...... f human prostate cancer cells.

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P2093

Hallgeir Rui

http://www.w3.org/2001/XMLSchema#string

Jianqiong Zhu

http://www.w3.org/2001/XMLSchema#string

Jianwu Xie

http://www.w3.org/2001/XMLSchema#string

Kalle Alanen

http://www.w3.org/2001/XMLSchema#string

Marja T Nevalainen

http://www.w3.org/2001/XMLSchema#string

Martti Nurmi

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Matthew J LeBaron

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Tommi J Ahonen

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P2860

Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation

Epithelial defect in prostates of Stat5a-null mice

STATs and gene regulation

Biochemical pathways of caspase activation during apoptosis.

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

Four deaths and a funeral: from caspases to alternative mechanisms.

Virus-based gene delivery systems.

Gene therapy progress and prospects: nonviral vectors.

Prolactin and prolactin receptors are expressed and functioning in human prostate.

Estrogen and prolactin regulation of rat dorsal and lateral prostate in organ culture.

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10784335

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12719422

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