APP metabolism regulates tau proteostasis in human cerebral cortex neurons
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Intracerebral haemorrhage in Down syndrome: protected or predisposed?The amyloid hypothesis of Alzheimer's disease at 25 yearsDissecting Alzheimer disease in Down syndrome using mouse modelsA genetic cause of Alzheimer disease: mechanistic insights from Down syndromeAlzheimer's in 3D culture: challenges and perspectivesAdvances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative Diseases3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders.N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42Stem cell models of Alzheimer's disease: progress and challenges.Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK3β signaling pathway.Qualitative changes in human γ-secretase underlie familial Alzheimer's disease.Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APPPartial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.Increased amyloidogenic APP processing in APOE ɛ4-negative individuals with cerebral β-amyloidosis.Increased CSF neurogranin concentration is specific to Alzheimer disease.Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications.Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research?Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations.Induced pluripotent stem cells as a discovery tool for Alzheimer׳s disease.Inhibition of Poly(ADP-ribose) Polymerase-1 Enhances Gene Expression of Selected Sirtuins and APP Cleaving Enzymes in Amyloid Beta Cytotoxicity.Induced pluripotent stem cell technology: a decade of progress.Applying fluid biomarkers to Alzheimer's disease.Modeling tau pathology in human stem cell derived neurons.Phenotypic Screening Identifies Modulators of Amyloid Precursor Protein Processing in Human Stem Cell Models of Alzheimer's Disease.Erratum to: Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research?CRISPR Transcriptional Activation Analysis Unmasks an Occult γ-Secretase Processivity Defect in Familial Alzheimer's Disease Skin Fibroblasts.Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.Importance of tau in cognitive decline as revealed by developmental exposure to lead.Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease.Stem Cell Technology for (Epi)genetic Brain Disorders.Dysregulation of Rab5-Mediated Endocytic Pathways in Alzheimer's Disease.Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease.Skeletal Muscle CLARITY: A Preliminary Study of Imaging The Three-Dimensional Architecture of Blood Vessels and Neurons.Recent Advances: Decoding Alzheimer's Disease With Stem Cells.Alzheimer's Disease: Insights from Genetic Mouse Models and Current Advances in Human IPSC-Derived Neurons.Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios.Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity.IgM response against amyloid-beta in aging: a potential peripheral protective mechanism
P2860
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P2860
APP metabolism regulates tau proteostasis in human cerebral cortex neurons
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
APP metabolism regulates tau proteostasis in human cerebral cortex neurons
@en
type
label
APP metabolism regulates tau proteostasis in human cerebral cortex neurons
@en
prefLabel
APP metabolism regulates tau proteostasis in human cerebral cortex neurons
@en
P2093
P2860
P50
P1433
P1476
APP metabolism regulates tau proteostasis in human cerebral cortex neurons
@en
P2093
Amelia McGlade
Frederick J Livesey
Lewis D B Evans
Tatyana B Dias
Therese Andersson
P2860
P304
P356
10.1016/J.CELREP.2015.03.068
P50
P577
2015-04-23T00:00:00Z