Benzo[alpha]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNA.
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Detection of phosphodiester adducts formed by the reaction of benzo[a]pyrene diol epoxide with 2'-deoxynucleotides using collision-induced dissociation electrospray ionization tandem mass spectrometryMismatch repair processing of carcinogen-DNA adducts triggers apoptosisImpact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons.Carcinogenic epoxides of benzo[a]pyrene and cyclopenta[cd]pyrene induce base substitutions via specific transversions.Oxidation of DNA bases by tumor promoter-activated processes.Formation and persistence of benzo(a)pyrene metabolite-DNA adducts.Approach to risk assessment for genotoxic carcinogens based on data from the mouse skin initiation-promotion model.Identification of the major adducts formed by reaction of benzo(a)pyrene diol epoxide with DNA in vitroInduction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis.Benzo[a]pyrene diol epoxide-DNA cis adduct formation through a trans chlorohydrin intermediate.Hydrolysis of benzo[a]pyrene diol epoxide and its covalent binding to DNA proceed through similar rate-determining steps.Base insertion and deletion mutations induced in an Escherichia coli plasmid by benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxideKinds and spectrum of mutations induced by 1-nitrosopyrene adducts during plasmid replication in human cellsSolution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNAIn vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic micePhotochemistry and photobiology of psoralens.Generation of nucleic acid structures and binding of molecules to DNA.Aryl hydrocarbon hydroxylase and benzo[a] pyrene metabolism in rodent liver and human cels.Xenobiotic metabolism by prostaglandin endoperoxide synthetase.Metabolic activation of 7,8-dihydroxy-7,8-dihydrobenzo[a]-pyrene during prostaglandin biosynthesis.Mutagenic and carcinogenic effects of pesticides.Repair-Resistant DNA Lesions.Sites of inhibition of in vitro DNA synthesis in carcinogen- and UV-treated phi X174 DNA.Genomic analysis of cancer tissue reveals that somatic mutations commonly occur in a specific motif.Quantitative comparison of initiation and mutation phenotypes in hepatocytes of the analbuminemic rat.Interactions of molecules with nucleic acids. X. Covalent intercalative binding of the carcinogenic BPDE I(+) to kinked DNA.Toxic agents resulting from the oxidative metabolism of steroid hormones and drugs.Characterization and Quantitation of Benzo[A]pyrene-DNA Adducts by Solid-Matrix LuminescenceDouble-stranded DNA stereoselectively binds benzo(a)pyrene diol epoxides
P2860
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P2860
Benzo[alpha]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNA.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年論文
@yue
1977年論文
@zh-hant
1977年論文
@zh-hk
1977年論文
@zh-mo
1977年論文
@zh-tw
1977年论文
@wuu
1977年论文
@zh
1977年论文
@zh-cn
name
Benzo[alpha]pyrene diol epoxid ...... ine and deoxyadenosine in DNA.
@en
type
label
Benzo[alpha]pyrene diol epoxid ...... ine and deoxyadenosine in DNA.
@en
prefLabel
Benzo[alpha]pyrene diol epoxid ...... ine and deoxyadenosine in DNA.
@en
P2093
P356
P1433
P1476
Benzo[alpha]pyrene diol epoxid ...... ine and deoxyadenosine in DNA.
@en
P2093
P2888
P304
P356
10.1038/269725A0
P407
P577
1977-10-01T00:00:00Z
P6179
1013295688