Modulation of Rac1 and ARF6 activation during epithelial cell scattering.
about
The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasionGEP100/BRAG2: activator of ADP-ribosylation factor 6 for regulation of cell adhesion and actin cytoskeleton via E-cadherin and alpha-cateninARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-actin rosettes in breast cancer cells in response to epidermal growth factorCrucial role of the small GTPase ARF6 in hepatic cord formation during liver developmentThe scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration.ARF-GEF cytohesin-2/ARNO regulates R-Ras and α5-integrin recycling through an EHD1-positive compartmentGEP100/Arf6 is required for epidermal growth factor-induced ERK/Rac1 signaling and cell migration in human hepatoma HepG2 cellsRegulation of actin cytoskeleton dynamics by Arf-family GTPases.GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration.The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility.Arf6 recruits the Rac GEF Kalirin to the plasma membrane facilitating Rac activation.Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis.The guanine nucleotide exchange protein for ADP-ribosylation factor 6, ARF-GEP100/BRAG2, regulates phagocytosis of monocytic phagocytes in an ARF6-dependent process.An effector domain mutant of Arf6 implicates phospholipase D in endosomal membrane recycling.Cdc42 localization and cell polarity depend on membrane trafficThe cytohesin coiled-coil domain interacts with threonine 276 to control membrane association.The cross-Rho'ds of cell-cell adhesion.The GTPase ARF6 Controls ROS Production to Mediate Angiotensin II-Induced Vascular Smooth Muscle Cell ProliferationADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages.GGA3 mediates TrkA endocytic recycling to promote sustained Akt phosphorylation and cell survival.Modeling the Transitions between Collective and Solitary Migration Phenotypes in Cancer Metastasis.Establishing epithelial glandular polarity: interlinked roles for ARF6, Rac1, and the matrix microenvironment.Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation.Arf GAPs as regulators of the actin cytoskeleton.ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epitheliaADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway.How important are Rho GTPases in neurosecretion?Protein-protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1.Non-neuronal functions of the m2 muscarinic acetylcholine receptor.Epithelial-to-Mesenchymal Plasticity Harnesses Endocytic Circuitries.ADP ribosylation factor 6 (Arf6) acts through FilGAP protein to down-regulate Rac protein and regulates plasma membrane blebbing.Rab11-FIP3 is a Rab11-binding protein that regulates breast cancer cell motility by modulating the actin cytoskeleton.Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling.Involvement of Rab13 and JRAB/MICAL-L2 in epithelial cell scattering.Tumor suppressor in lung cancer (TSLC)1 suppresses epithelial cell scattering and tubulogenesis.The Listeria protein internalin B mimics hepatocyte growth factor-induced receptor trafficking.Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitionsProteasome-mediated degradation of Rac1-GTP during epithelial cell scattering.
P2860
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P2860
Modulation of Rac1 and ARF6 activation during epithelial cell scattering.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Modulation of Rac1 and ARF6 activation during epithelial cell scattering.
@en
type
label
Modulation of Rac1 and ARF6 activation during epithelial cell scattering.
@en
prefLabel
Modulation of Rac1 and ARF6 activation during epithelial cell scattering.
@en
P2860
P356
P1476
Modulation of Rac1 and ARF6 activation during epithelial cell scattering.
@en
P2093
Crislyn D'Souza-Schorey
Felipe Palacios
P2860
P304
17395-17400
P356
10.1074/JBC.M300998200
P407
P577
2003-02-27T00:00:00Z