Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3.
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CART peptides as modulators of dopamine and psychostimulants and interactions with the mesolimbic dopaminergic systemCocaine- and amphetamine-regulated transcript peptides play a role in drug abuse and are potential therapeutic targetsCART in the regulation of appetite and energy homeostasisCART peptides: regulators of body weight, reward and other functionsSecretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity.Characterisation of CART-containing neurons and cells in the porcine pancreas, gastro-intestinal tract, adrenal and thyroid glands.Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake.Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics.Biochemical and cell biological properties of the human prohormone convertase 1/3 Ser357Gly mutation: a PC1/3 hypermorph.The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats.An amphipathic alpha-helix in the prodomain of cocaine and amphetamine regulated transcript peptide precursor serves as its sorting signal to the regulated secretory pathway.GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1)Characterization of the Two CART Genes (CART1 and CART2) in Chickens (Gallus gallus).Cocaine-and Amphetamine Regulated Transcript (CART) Peptide Is Expressed in Precursor Cells and Somatotropes of the Mouse Pituitary GlandCocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin-releasing hormonePCSK1 Variants and Human Obesity.RNAi-mediated silencing of prohormone convertase (PC) 5/6 expression leads to impairment in processing of cocaine- and amphetamine-regulated transcript (CART) precursor.Immunohistochemical localization of cocaine- and amphetamine-regulated transcript peptide (CARTp) in the brain of the pigeon (Columba livia) and zebra finch (Taeniopygia guttata).Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor.Altered proglucagon processing in an alpha-cell line derived from prohormone convertase 2 null mouse islets.Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion.Neuropeptidomic analysis establishes a major role for prohormone convertase-2 in neuropeptide biosynthesis.CART neurons in the arcuate nucleus and lateral hypothalamic area exert differential controls on energy homeostasis.PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus).Nicotine regulates cocaine-amphetamine-Regulated Transcript (Cart) in the mesocorticolimbic system.
P2860
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P2860
Biological processing of the cocaine and amphetamine-regulated transcript precursors by prohormone convertases, PC2 and PC1/3.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Biological processing of the c ...... ne convertases, PC2 and PC1/3.
@en
type
label
Biological processing of the c ...... ne convertases, PC2 and PC1/3.
@en
prefLabel
Biological processing of the c ...... ne convertases, PC2 and PC1/3.
@en
P2093
P2860
P356
P1476
Biological processing of the c ...... ne convertases, PC2 and PC1/3.
@en
P2093
Arunangsu Dey
Christopher W Turck
Donald F Steiner
Jeffrey Stein
Raymond Carroll
Xiaorong Xhu
P2860
P304
15007-15014
P356
10.1074/JBC.M212128200
P407
P577
2003-02-12T00:00:00Z