Synthesis and functional analyses of nuclear clusterin, a cell death protein.
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Apolipoprotein J (clusterin) activates rodent microglia in vivo and in vitroHuman nuclear clusterin mediates apoptosis by interacting with Bcl-XL through C-terminal coiled coil domainPACAP inhibits tumor growth and interferes with clusterin in cervical carcinomasClusterin inhibits apoptosis by interacting with activated BaxClusterin: a key player in cancer chemoresistance and its inhibitionInterleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progressionNew insights into the mechanisms of green tea catechins in the chemoprevention of prostate cancerClusterin: Review of research progress and looking ahead to direction in hepatocellular carcinomaNon-secreted clusterin isoforms are translated in rare amounts from distinct human mRNA variants and do not affect Bax-mediated apoptosis or the NF-κB signaling pathwayRole of Chemotherapy and Mechanisms of Resistance to Chemotherapy in Metastatic Castration-Resistant Prostate CancerPlasma Clusterin and Lipid Profile: A Link with Aging and Cardiovascular Diseases in a Population with a Consistent Number of CentenariansNuclear clusterin is associated with neuronal apoptosis in the developing rat brain upon ethanol exposureClusterin expression in normal mucosa and colorectal cancer.Development of reverse phase protein microarrays for the validation of clusterin, a mid-abundant blood biomarkerEffects of clusterin over-expression on metastatic progression and therapy in breast cancer.Clusterin is a potential lymphotoxin beta receptor target that is upregulated and accumulates in germinal centers of mouse spleen during immune response.Advances and challenges in basic and translational research on clusterinAscorbate induces apoptosis in melanoma cells by suppressing Clusterin expression.Molecular imaging of breast tumors using a near-infrared fluorescently labeled clusterin binding peptide.Genetics of clusterin isoform expression and Alzheimer's disease risk.pVHL mediates K63-linked ubiquitination of nCLU.Isolation and characterization of a novel gene CLUAP1 whose expression is frequently upregulated in colon cancer.Inhibition of intracellular clusterin attenuates cell death in nephropathic cystinosis.Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer.Expression of novel Alzheimer's disease risk genes in control and Alzheimer's disease brains.CLU blocks HDACI-mediated killing of neuroblastoma.Exon-skipping strategy by ratio modulation between cytoprotective versus pro-apoptotic clusterin forms increased sensitivity of LNCaP to cell death.Se-methylselenocysteine inhibits apoptosis induced by clusterin knockdown in neuroblastoma N2a and SH-SY5Y cell lines.Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complexOncogenic role of clusterin overexpression in multistage colorectal tumorigenesis and progressionClusterin confers gemcitabine resistance in pancreatic cancerProapoptotic role of nuclear clusterin in brain.CRM1 protein-mediated regulation of nuclear clusterin (nCLU), an ionizing radiation-stimulated, Bax-dependent pro-death factormda-7/IL-24 differentially regulates soluble and nuclear clusterin in prostate cancer.Effects of female sex hormones on clusterin expression and paclitaxel resistance in endometrial cancer cell linesClusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7BClusterin attenuates the development of renal fibrosis.Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations.Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation.Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling.
P2860
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P2860
Synthesis and functional analyses of nuclear clusterin, a cell death protein.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Synthesis and functional analyses of nuclear clusterin, a cell death protein.
@en
type
label
Synthesis and functional analyses of nuclear clusterin, a cell death protein.
@en
prefLabel
Synthesis and functional analyses of nuclear clusterin, a cell death protein.
@en
P2093
P2860
P356
P1476
Synthesis and functional analyses of nuclear clusterin, a cell death protein.
@en
P2093
David A Boothman
Dmitry Y Klokov
Konstantin S Leskov
Timothy J Kinsella
P2860
P304
11590-11600
P356
10.1074/JBC.M209233200
P407
P577
2003-01-24T00:00:00Z