Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation.
about
Pain and Poppies: The Good, the Bad, and the Ugly of Opioid AnalgesicsNT5E mutations that cause human disease are associated with intracellular mistrafficking of NT5E proteinPain-relieving prospects for adenosine receptors and ectonucleotidases.Cellular function and molecular structure of ecto-nucleotidases.Central or peripheral delivery of an adenosine A1 receptor agonist improves mechanical allodynia in a mouse model of painful diabetic neuropathyPAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosineAMP is an adenosine A1 receptor agonistEctonucleotidases in solid organ and allogeneic hematopoietic cell transplantationOrally active adenosine A(1) receptor agonists with antinociceptive effects in mice.Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.Allosteric interactions at adenosine A(1) and A(3) receptors: new insights into the role of small molecules and receptor dimerization.Therapeutic potentials of ecto-nucleoside triphosphate diphosphohydrolase, ecto-nucleotide pyrophosphatase/phosphodiesterase, ecto-5'-nucleotidase, and alkaline phosphatase inhibitors.Acupuncture-Induced Analgesia: A Neurobiological Basis in Purinergic Signaling.Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model.Crystallization and preliminary X-ray analysis of the open form of human ecto-5'-nucleotidase (CD73)Characterization and turnover of CD73/IP(3)R3-positive microvillar cells in the adult mouse olfactory epithelium.Sustained Elevated Adenosine via ADORA2B Promotes Chronic Pain through Neuro-immune Interaction.Emerging roles for ectonucleotidases in pain-sensing neurons.The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin.Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling.Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models
P2860
Q26782928-936F19EF-EAFF-46A8-852A-D5144411825CQ28539242-A3F85678-D3AB-430E-A09B-E4D0E3C4C291Q34025341-3ED465B2-9A3C-4037-AAEB-CAD636D5CC3FQ34031794-5535F54C-F8AB-42E9-8F94-02CF08D93D1AQ34855100-DECCB98D-BB67-46FD-923F-0A8B92A52F40Q35533525-850E1AC2-521A-4339-B592-6FBEADEE6B74Q35773917-C0E7405B-EA2C-4013-8062-A98DE5CBDA4AQ36350059-99F91714-C843-4EC7-9BBC-F09BB8CABD81Q36408152-FC2D8AF9-8A76-448C-B48E-872FEDA0703AQ37032505-435997A9-ADA0-42F4-AA27-7876B3B44DCEQ38136285-5068A8AD-217E-4D4D-90DC-7A207EFDCC63Q38151635-FF4D3CBA-7B42-44AD-BA52-CB9FBA52F52BQ38799466-C6D85A86-5ADF-456F-9749-3806C5CEFACCQ40378596-FA945946-615E-4ABE-8E81-15EFEC679439Q42144009-B1B3B332-F71E-4000-B658-89985643B048Q42512260-F87F4FF5-E71F-4141-BC78-48B738D34CF6Q42601497-507C07E4-10FF-4EF7-911E-2B6681AAB84CQ42682386-CADCD803-B6A3-4DF3-9CC0-B991A4D163D1Q46837128-926093E6-00A0-4268-B037-D7ACFAEE03B4Q48237724-9E419DFE-C52A-42FC-A3BC-88A338083437Q57132589-76B59D60-F454-4C5D-B258-277505208DEC
P2860
Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Recombinant ecto-5'-nucleotida ...... nosine A1 receptor activation.
@en
type
label
Recombinant ecto-5'-nucleotida ...... nosine A1 receptor activation.
@en
prefLabel
Recombinant ecto-5'-nucleotida ...... nosine A1 receptor activation.
@en
P2093
P2860
P356
P1433
P1476
Recombinant ecto-5'-nucleotida ...... nosine A1 receptor activation.
@en
P2093
Mark J Zylka
Meagen K Voss
Nathaniel A Sowa
P2860
P2888
P356
10.1186/1744-8069-6-20
P577
2010-04-14T00:00:00Z
P5875
P6179
1004294389