ZD6126: a novel small molecule vascular targeting agent.
about
Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenograftsEnhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRITumour biomechanical response to the vascular disrupting agent ZD6126 in vivo assessed by magnetic resonance elastographyDiscovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.Correlation of MRI biomarkers with tumor necrosis in Hras5 tumor xenograft in athymic ratsPhase I clinical evaluation of ZD6126, a novel vascular-targeting agent, in patients with solid tumors.Role of the cytoskeleton in formation and maintenance of angiogenic sproutsEvaluation of tumor ischemia in response to an indole-based vascular disrupting agent using BLI and (19)F MRI.Vascular targeting agents.Review of the effects of anti-angiogenic compounds on the epiphyseal growth plate.Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma.The microtubule as a breast cancer target.Tumor vasculature as target for therapeutic intervention.Antivascular effects of TZT-1027 (Soblidotin) on murine Colon26 adenocarcinoma.Enhanced vesicular stomatitis virus (VSVΔ51) targeting of head and neck cancer in combination with radiation therapy or ZD6126 vascular disrupting agent.Biological evaluation of benzosuberones.Effect of pretreatment with atenolol and nifedipine on ZD6126-induced cardiac toxicity in rats.Realizing the Potential of Vascular Targeted Therapy: The Rationale for Combining Vascular Disrupting Agents and Anti-Angiogenic Agents to Treat Cancer.
P2860
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P2860
ZD6126: a novel small molecule vascular targeting agent.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
ZD6126: a novel small molecule vascular targeting agent.
@en
type
label
ZD6126: a novel small molecule vascular targeting agent.
@en
prefLabel
ZD6126: a novel small molecule vascular targeting agent.
@en
P2093
P1476
ZD6126: a novel small molecule vascular targeting agent.
@en
P2093
Anderson J Ryan
David C Blakey
F Russell Westwood
Mike Walker
Susan E Ashton
P304
P356
10.1016/S0360-3016(02)03922-6
P407
P577
2002-12-01T00:00:00Z