BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases. - Wikidata - wikimedia - TriplyDB

BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.

BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.

http://www.wikidata.org/entity/Q40691704

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Molecular mechanisms involved in farnesol-induced apoptosis Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activity Deletion of Bid impedes cell proliferation and hepatic carcinogenesis Bcl-2 protein expression is associated with p27 and p53 protein expressions and MIB-1 counts in breast cancer p27 deficiency cooperates with Bcl-2 but not Bax to promote T-cell lymphoma.Initiation of premature senescence by Bcl-2 in hypoxic condition.Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice.The immunoglobulin heavy chain gene 3' enhancers induce Bcl2 deregulation and lymphomagenesis in murine B cells.The Bcl-2 family: roles in cell survival and oncogenesis.Sperm-borne microRNA-34c is required for the first cleavage division in mouse Selective Impairment of TH17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes Apoptosis in normal and diseased oral tissues.Loss of Bcl-x in Ph+ B-ALL increases cellular proliferation and does not inhibit leukemogenesis MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.Does the expression of BCL2 have prognostic significance in malignant peritoneal mesothelioma?Microarray and pathway analysis reveals decreased CDC25A and increased CDC42 associated with slow growth of BCL2 overexpressing immortalized breast cell line.Ki67-BCL2 index in prognosis of malignant peritoneal mesothelioma.Bcl-X(L) is the primary mediator of p21 protection against hyperoxia-induced cell death Nickel compounds induce apoptosis in human bronchial epithelial Beas-2B cells by activation of c-Myc through ERK pathway Regulation of B-cell entry into the cell cycle Protect and serve: Bcl-2 proteins as guardians and rulers of cancer cell survival.Cell death in mammalian cell culture: molecular mechanisms and cell line engineering strategies c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis.High Ki67/BCL2 index is associated with worse outcome in early stage breast cancer.Loss of BCL-2 in the progression of oral cancer is not attributable to mutations.BOK displays cell death-independent tumor suppressor activity in non-small-cell lung carcinoma.Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.Upregulation of SRF Is Associated With Hypoxic Pulmonary Hypertension by Promoting Viability of Smooth Muscle Cells via Increasing Expression of Bcl-2.Revisiting the role of MCL1 in tumorigenesis of solid cancer: gene expression correlates with antiproliferative phenotype in breast cancer cells and its functional regulatory variants are associated with reduced cancer susceptibility.Obatoclax induces G1/G0-phase arrest via p38/p21(waf1/Cip1) signaling pathway in human esophageal cancer cells.BCL-XL mediates the strong selective advantage of a 20q11.21 amplification commonly found in human embryonic stem cell cultures.Effect of silencing of high mobility group A2 gene on gastric cancer MKN-45 cells.Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung.Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry.BCL-2 translation is mediated via internal ribosome entry during cell stress.Predicting essential genes and synthetic lethality via influence propagation in signaling pathways of cancer cell fates.G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.Bcl-2 blocks 2-methoxyestradiol induced leukemia cell apoptosis by a p27(Kip1)-dependent G1/S cell cycle arrest in conjunction with NF-kappaB activation.Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance.

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BCL-x(L) and BCL2 delay Myc-induced cell cycle entry through elevation of p27 and inhibition of G1 cyclin-dependent kinases.

http://www.wikidata.org/entity/Q40691704

description

2002 nî lūn-bûn

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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2002年论文

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2002年论文

@zh-cn

name

BCL-x(L) and BCL2 delay Myc-in ...... f G1 cyclin-dependent kinases.

@en

type

label

BCL-x(L) and BCL2 delay Myc-in ...... f G1 cyclin-dependent kinases.

@en

prefLabel

BCL-x(L) and BCL2 delay Myc-in ...... f G1 cyclin-dependent kinases.

@en

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BCL-x(L) and BCL2 delay Myc-in ...... f G1 cyclin-dependent kinases.

@en

P2093

Anuja Chattopadhyay

http://www.w3.org/2001/XMLSchema#string

Christina Parkhurst

http://www.w3.org/2001/XMLSchema#string

Courtney Greider

http://www.w3.org/2001/XMLSchema#string

Elizabeth Yang

http://www.w3.org/2001/XMLSchema#string

P2860

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

Different roles for cyclins D1 and E in regulation of the G1-to-S transition

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

Induction of apoptosis in fibroblasts by c-myc protein

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

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scholarly article

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10.1038/SJ.ONC.1205928

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51

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21

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1035936002

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12420213

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