Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells.
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Pancreatic regulation of glucose homeostasisNutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cellsGlucose-dependent insulinotropic polypeptide-mediated up-regulation of beta-cell antiapoptotic Bcl-2 gene expression is coordinated by cyclic AMP (cAMP) response element binding protein (CREB) and cAMP-responsive CREB coactivator 2The entero-insular axis: implications for human metabolism.Antidiabetic potential of two novel fatty acid derivatised, N-terminally modified analogues of glucose-dependent insulinotropic polypeptide (GIP): N-AcGIP(LysPAL16) and N-AcGIP(LysPAL37).A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control.Transcriptional analysis of apoptotic cerebellar granule neurons following rescue by gastric inhibitory polypeptideGIP and GLP-1, the two incretin hormones: Similarities and differencesThe incretin system and cardiometabolic diseasePostnatal development of numbers and mean sizes of pancreatic islets and beta-cells in healthy mice and GIPR(dn) transgenic diabetic mice.Glucose-dependent insulinotropic polypeptide stimulates the proliferation of colorectal cancer cells.A novel long-acting glucose-dependent insulinotropic peptide analogue: enhanced efficacy in normal and diabetic rodentsAlogliptin: a new addition to the class of DPP-4 inhibitors.The role of incretins in glucose homeostasis and diabetes treatment.Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation.Activation of the GLP-1 receptor signalling pathway: a relevant strategy to repair a deficient beta-cell massThe role of gut hormones in glucose homeostasisEffects of High Glucose Levels and Glycated Serum on GIP Responsiveness in the Pancreatic Beta Cell Line HIT-T15.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationBicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain.Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation.Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.Rationale for dipeptidyl peptidase 4 inhibitors: a new class of oral agents for the treatment of type 2 diabetes mellitus.Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocinTargeting beta-cell mass in type 2 diabetes: promise and limitations of new drugs based on incretinsProtein hydrolysates in sports nutrition.Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease?Gastrointestinal hormones and the regulation of β-cell mass.The emerging role of the intestine in metabolic diseases.Glucose-dependent insulinotropic polypeptide: from pathophysiology to therapeutic opportunities in obesity-associated disorders.Nutrient detection by incretin hormone secreting cellsAlogliptin benzoate for the treatment of type 2 diabetes.Incretin hormones and beta-cell mass expansion: what we know and what is missing?DPP-4 inhibitors: focus on safety.Daily administration of the GIP-R antagonist (Pro3)GIP in streptozotocin-induced diabetes suggests that insulin-dependent mechanisms are critical to anti-obesity-diabetes actions of (Pro3)GIP.An enzymatically stable GIP/xenin hybrid peptide restores GIP sensitivity, enhances beta cell function and improves glucose homeostasis in high-fat-fed mice.Noncanonical activation of Akt/protein kinase B in {beta}-cells by the incretin hormone glucose-dependent insulinotropic polypeptide.Glucose intolerance and reduced proliferation of pancreatic beta-cells in transgenic pigs with impaired glucose-dependent insulinotropic polypeptide function.Inhibition of GSK3 promotes replication and survival of pancreatic beta cells.Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP.
P2860
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P2860
Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mechanisms of mitogenic and an ...... ypeptide in beta(INS-1)-cells.
@en
type
label
Mechanisms of mitogenic and an ...... ypeptide in beta(INS-1)-cells.
@en
prefLabel
Mechanisms of mitogenic and an ...... ypeptide in beta(INS-1)-cells.
@en
P2093
P356
P1476
Mechanisms of mitogenic and an ...... ypeptide in beta(INS-1)-cells.
@en
P2093
P304
P356
10.1677/JOE.0.1740233
P407
P577
2002-08-01T00:00:00Z