Molecular cloning, distribution and functional analysis of the NA(V)1.6. Voltage-gated sodium channel from human brain.
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Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodentsAxon-somatic back-propagation in detailed models of spinal alpha motoneuronsPerisomatic voltage-gated sodium channels actively maintain linear synaptic integration in principal neurons of the medial superior olive.Excitability constraints on voltage-gated sodium channelsTarget promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels.Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchangerBinding specificity of sea anemone toxins to Nav 1.1-1.6 sodium channels: unexpected contributions from differences in the IV/S3-S4 outer loop.Resurgent current and voltage sensor trapping enhanced activation by a beta-scorpion toxin solely in Nav1.6 channel. Significance in mice Purkinje neurons.Ankyrin-G regulates inactivation gating of the neuronal sodium channel, Nav1.6.Functional properties and differential neuromodulation of Na(v)1.6 channels.Alternative splicing modulates inactivation of type 1 voltage-gated sodium channels by toggling an amino acid in the first S3-S4 linker.Differential state-dependent modification of rat Na(v)1.6 sodium channels expressed in human embryonic kidney (HEK293) cells by the pyrethroid insecticides tefluthrin and deltamethrin.Amyloid precursor protein enhances Nav1.6 sodium channel cell surface expressionMolecular and functional differences in voltage-activated sodium currents between GABA projection neurons and dopamine neurons in the substantia nigraHuman Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.From Squid to Mammals with the HH Model through the Nav Channels' Half-Activation-Voltage Parameter.Loss of Na+ channel beta2 subunits is neuroprotective in a mouse model of multiple sclerosis.Amyloid precursor protein modulates Nav1.6 sodium channel currents through a Go-coupled JNK pathway.RING1B contributes to Ewing sarcoma development by repressing the NaV1.6 sodium channel and the NF-κB pathway, independently of the fusion oncoprotein.Properties of human brain sodium channel α-subunits expressed in HEK293 cells and their modulation by carbamazepine, phenytoin and lamotrigineThe association of bacterial C9-based TTX-like compounds with Prorocentrum minimum opens new uncertainties about shellfish seafood safety.A single Markov-type kinetic model accounting for the macroscopic currents of all human voltage-gated sodium channel isoforms.The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms.The importance of being profiled: improving drug candidate safety and efficacy using ion channel profiling.Voltage-gated sodium channel isoform-specific effects of pompilidotoxins.Membrane trauma and Na+ leak from Nav1.6 channels.Carbamazepine and topiramate modulation of transient and persistent sodium currents studied in HEK293 cells expressing the Na(v)1.3 alpha-subunit.Functional expression of Rat Nav1.6 voltage-gated sodium channels in HEK293 cells: modulation by the auxiliary β1 subunit.Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis.Axo-somatic and apical dendritic Kv7/M channels differentially regulate the intrinsic excitability of adult rat CA1 pyramidal cells.Coupled left-shift of Nav channels: modeling the Na⁺-loading and dysfunctional excitability of damaged axons.The invasiveness of human cervical cancer associated to the function of Na1.6 channels is mediated by MMP-2 activity
P2860
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P2860
Molecular cloning, distribution and functional analysis of the NA(V)1.6. Voltage-gated sodium channel from human brain.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Molecular cloning, distributio ...... dium channel from human brain.
@en
type
label
Molecular cloning, distributio ...... dium channel from human brain.
@en
prefLabel
Molecular cloning, distributio ...... dium channel from human brain.
@en
P2093
P1476
Molecular cloning, distributio ...... dium channel from human brain.
@en
P2093
Andrew J Powell
Jeffrey J Clare
Michael A Romanos
Stephen A Burbidge
Timothy J Dale
William R J Whitaker
Xin Min Xie
P356
10.1016/S0169-328X(02)00188-2
P577
2002-06-01T00:00:00Z