Regulation of endogenous gene expression with a small-molecule dimerizer.
about
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificitiesDistinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosisPatterning expression of regenerative growth factors using high intensity focused ultrasoundA time- and dose-dependent STAT1 expression system.Characterization of a molecular switch system that regulates gene expression in mammalian cells through a small molecule.Zinc finger nucleases as tools to understand and treat human diseases.Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors.Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factorsConditional human VEGF-mediated vascularization in chicken embryos using a novel temperature-inducible gene regulation (TIGR) systemStreptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice.Gene therapy progress and prospects: transcription regulatory systems.Development of pro-angiogenic engineered transcription factors for the treatment of cardiovascular disease.Synthetic zinc finger peptides: old and novel applications.Locked and proteolysis-based transcription activator-like effector (TALE) regulationDrug-inducible and simultaneous regulation of endogenous genes by single-chain nuclear receptor-based zinc-finger transcription factor gene switches.Selective DNA-binding by designed bisbenzamidine-homeodomain chimeras.Sequence-selective DNA recognition with peptide-bisbenzamidine conjugates.Modes of TAL effector-mediated repression.A chemical switch for controlling viral infectivity.Spatiotemporal control of vascular endothelial growth factor expression using a heat-shock-activated, rapamycin-dependent gene switch.Orthogonal control of endogenous gene expression in mammalian cells using synthetic ligands.Suppression of gene expression by a cell-permeable Tet repressor.Synthetic protein-protein interaction domains created by shuffling Cys2His2 zinc-fingers.Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling.Regulation of CCR7-dependent cell migration through CCR7 homodimer formation.Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesis.Small molecule control of pre-mRNA splicing.A designed DNA binding motif that recognizes extended sites and spans two adjacent major groovesProgrammed stereoselective assembly of DNA-binding helical metallopeptides
P2860
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P2860
Regulation of endogenous gene expression with a small-molecule dimerizer.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Regulation of endogenous gene expression with a small-molecule dimerizer.
@en
type
label
Regulation of endogenous gene expression with a small-molecule dimerizer.
@en
prefLabel
Regulation of endogenous gene expression with a small-molecule dimerizer.
@en
P2093
P2860
P356
P1433
P1476
Regulation of endogenous gene expression with a small-molecule dimerizer.
@en
P2093
Katja Linher
Maryann Giel
Roy Pollock
Tim Clackson
P2860
P2888
P304
P356
10.1038/NBT0702-729
P577
2002-07-01T00:00:00Z