Clusterin (SGP-2) transient overexpression decreases proliferation rate of SV40-immortalized human prostate epithelial cells by slowing down cell cycle progression.
about
Non-secreted clusterin isoforms are translated in rare amounts from distinct human mRNA variants and do not affect Bax-mediated apoptosis or the NF-κB signaling pathwayA novel gene signature for molecular diagnosis of human prostate cancer by RT-qPCR.Lineage-specific restraint of pituitary gonadotroph cell adenoma growth.Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer.Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein.Multidimensional liquid chromatography platform for profiling alterations of clusterin N-glycosylation in the plasma of patients with renal cell carcinoma.Regulation of clusterin expression in mammary epithelial cellsRegulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis.Vanadium-induced apoptosis of HaCaT cells is mediated by c-fos and involves nuclear accumulation of clusterin.The role of stress proteins in prostate cancer.Hypoxia inducible factor-1α directly regulates nuclear clusterin transcription by interacting with hypoxia response elements in the clusterin promoterThe role of clusterin in Alzheimer's disease: pathways, pathogenesis, and therapy.DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.Clusterin overexpression in both malignant and nonmalignant prostate epithelial cells induces cell cycle arrest and apoptosisKnockdown of clusterin expression increases the in vitro sensitivity of human prostate cancer cells to paclitaxel.Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.Intracellular clusterin negatively regulates ovarian chemoresistance: compromised expression sensitizes ovarian cancer cells to paclitaxel.Clusterin and chemotherapy sensitivity under normoxic and graded hypoxic conditions in colorectal cancer.Cancer cell-derived clusterin modulates the phosphatidylinositol 3'-kinase-Akt pathway through attenuation of insulin-like growth factor 1 during serum deprivationCell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterinNuclear translocation of a clusterin isoform is associated with induction of anoikis in SV40-immortalized human prostate epithelial cells.Modulation of different clusterin isoforms in human colon tumorigenesis.Evaluation of serum clusterin as a surveillance tool for human hepatocellular carcinoma with hepatitis B virus related cirrhosis.Proteotranscriptomic measurements of E6-Associated Protein (E6AP) targets in DU145 prostate cancer cells.
P2860
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P2860
Clusterin (SGP-2) transient overexpression decreases proliferation rate of SV40-immortalized human prostate epithelial cells by slowing down cell cycle progression.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Clusterin (SGP-2) transient ov ...... g down cell cycle progression.
@en
type
label
Clusterin (SGP-2) transient ov ...... g down cell cycle progression.
@en
prefLabel
Clusterin (SGP-2) transient ov ...... g down cell cycle progression.
@en
P2093
P2860
P356
P1433
P1476
Clusterin (SGP-2) transient ov ...... ng down cell cycle progression
@en
P2093
Arnaldo Corti
Francesca Scorcioni
Maurizio Scaltriti
Pierpaola Davalli
Serenella Astancolle
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205594
P407
P577
2002-06-01T00:00:00Z
P5875
P6179
1001231841