Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion
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Psychophysiological effects of a web-based stress management system: a prospective, randomized controlled intervention study of IT and media workers [ISRCTN54254861].The plasminogen activation system and the regulation of catecholaminergic functionThe anti-fibrinolytic SERPIN, plasminogen activator inhibitor 1 (PAI-1), is targeted to and released from catecholamine storage vesiclesCathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptidesProteomics-based discovery of a novel, structurally unique, and developmentally regulated plasminogen receptor, Plg-RKT, a major regulator of cell surface plasminogen activationProteolytic cleavage of chromogranin A (CgA) by plasmin. Selective liberation of a specific bioactive CgA fragment that regulates catecholamine release.New insights into the role of Plg-RKT in macrophage recruitment.Catestatin: a multifunctional peptide from chromogranin APlasminogen promotes macrophage phagocytosis in miceLumenal protein within secretory granules affects fusion pore expansionNaturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease.Direct vasoactive effects of the chromogranin A (CHGA) peptide catestatin in humans in vivo.Monoclonal antibodies detect receptor-induced binding sites in Glu-plasminogen.The novel plasminogen receptor, plasminogen receptor(KT) (Plg-R(KT)), regulates catecholamine release.Regulation of macrophage migration by a novel plasminogen receptor Plg-R KT.Proteolytic cleavage of human chromogranin a containing naturally occurring catestatin variants: differential processing at catestatin region by plasmin.Novel peptide isomer strategy for stable inhibition of catecholamine release: application to hypertensionA new chromogranin A-dependent angiogenic switch activated by thrombin.Plasminogen receptors: the first quarter century.Peptidergic regulation of plasminogen activator inhibitor-1 gene expression in vivo.Chromogranin B: intra- and extra-cellular mechanisms to regulate catecholamine storage and release, in catecholaminergic cells and organisms.Chromogranin A as a biomarker in cardiovascular disease.The surging role of Chromogranin A in cardiovascular homeostasis.Deficiency of plasminogen receptor, Plg-RKT , causes defects in plasminogen binding and inflammatory macrophage recruitment in vivo.Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion.Specific interaction of angiostatin with integrin alpha(v)beta(3) in endothelial cells.Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin.The hippocampal cholinergic neurostimulating peptide, the N-terminal fragment of the secreted phosphatidylethanolamine-binding protein, possesses a new biological activity on cardiac physiology.Slow fusion pore expansion creates a unique reaction chamber for co-packaged cargo.Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells.
P2860
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P2860
Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Processing of chromogranin A b ...... lating catecholamine secretion
@en
type
label
Processing of chromogranin A b ...... lating catecholamine secretion
@en
prefLabel
Processing of chromogranin A b ...... lating catecholamine secretion
@en
P2093
P2860
P356
P1476
Processing of chromogranin A b ...... lating catecholamine secretion
@en
P2093
D T O'Connor
R J Parmer
S K Mahata
P2860
P304
P356
10.1172/JCI7394
P407
P577
2000-10-01T00:00:00Z