Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase.
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Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowthThe neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cellsEnteric nervous system development: migration, differentiation, and diseaseBuilding a second brain in the bowelPositive feedback between Cdc42 activity and H+ efflux by the Na-H exchanger NHE1 for polarity of migrating cellsParacrine regulation of pancreatic cancer cell invasion by peripheral nerves.Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migrationVitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation.Role of BDNF and GDNF in drug reward and relapse: a reviewPhosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform.RET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration.Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling.Identification of a key motif that determines the differential surface levels of RET and TrkB tyrosine kinase receptors and controls depolarization enhanced RET surface insertion.RET is a potential tumor suppressor gene in colorectal cancer.Structure and physiology of the RET receptor tyrosine kinase.Dynamic expression of neurotrophic factor receptors in postnatal spinal motoneurons and in mouse model of ALSNeurotrophic factor receptor RET: structure, cell biology, and inherited diseases.A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasiaHow to Treat a Signal? Current Basis for RET-Genotype-Oriented Choice of Kinase Inhibitors for the Treatment of Medullary Thyroid CancerDevelopment and developmental disorders of the enteric nervous system.The cAMP analogs have potent anti-proliferative effects on medullary thyroid cancer cell lines.Functional differences between GDNF-dependent and FGF2-dependent mouse spermatogonial stem cell self-renewal.The involvement of reactive oxygen species derived from NADPH oxidase-1 activation on the constitutive tyrosine auto-phosphorylation of RET proteins.The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesionProtein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.The RET and TRKA pathways collaborate to regulate neuroblastoma differentiation.Zic2 is required for enteric nervous system development and neurite outgrowth: a mouse model of enteric hyperplasia and dysplasia.Retinoic acid temporally orchestrates colonization of the gut by vagal neural crest cells.RET Gly691Ser mutation is associated with primary vesicoureteral reflux in the French-Canadian population from Quebec.The GDNF Family: A Role in Cancer?Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes.p66Shc regulates migration of castration-resistant prostate cancer cells.PKA phosphorylates RET:GDNF:GFRA dimerIdentification and characterization of two novel germline RET variants associated with medullary thyroid carcinoma.
P2860
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P2860
Novel mechanism of regulation of Rac activity and lamellipodia formation by RET tyrosine kinase.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Novel mechanism of regulation ...... mation by RET tyrosine kinase.
@en
type
label
Novel mechanism of regulation ...... mation by RET tyrosine kinase.
@en
prefLabel
Novel mechanism of regulation ...... mation by RET tyrosine kinase.
@en
P2093
P2860
P356
P1476
Novel mechanism of regulation ...... mation by RET tyrosine kinase.
@en
P2093
Kazutoshi Kiuchi
Masahide Takahashi
Toshifumi Fukuda
P2860
P304
19114-19121
P356
10.1074/JBC.M200643200
P407
P577
2002-03-08T00:00:00Z