Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium.
about
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and functionFunctional genomic screen for modulators of ciliogenesis and cilium lengthCiliary and centrosomal defects associated with mutation and depletion of the Meckel syndrome genes MKS1 and MKS3The primary cilium as a cellular signaling center: lessons from diseaseOFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblastsRenal cystic disease proteins play critical roles in the organization of the olfactory epitheliumThe exocyst protein Sec10 interacts with Polycystin-2 and knockdown causes PKD-phenotypesThe intraflagellar transport machinery of Chlamydomonas reinhardtii.Direct interactions of intraflagellar transport complex B proteins IFT88, IFT52, and IFT46.A conserved signal and GTPase complex are required for the ciliary transport of polycystin-1.Architecture and function of IFT complex proteins in ciliogenesisRegulation of calcium signaling by polycystin-2Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesisMechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminusThe primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationWnt9b signaling regulates planar cell polarity and kidney tubule morphogenesisGlomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney diseaseTargeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation controlCiliary proteins link basal body polarization to planar cell polarity regulationInhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells.Native polycystin 2 functions as a plasma membrane Ca2+-permeable cation channel in renal epitheliaEndothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1Fibrocystin/polyductin modulates renal tubular formation by regulating polycystin-2 expression and functionWhen cilia go bad: cilia defects and ciliopathiesKif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanismsAn ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations.Dicer regulates the development of nephrogenic and ureteric compartments in the mammalian kidney.miRNAs in mammalian ureteric bud development.XBX-1 encodes a dynein light intermediate chain required for retrograde intraflagellar transport and cilia assembly in Caenorhabditis elegans.Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene.Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathwayTransepithelial pressure pulses induce nucleotide release in polarized MDCK cells.Identification and sequence analysis of six new members of the NIMA-related kinase family in Chlamydomonas.Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-Similar3 (glis3) gene.Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.Knockdown of bicaudal C in zebrafish (Danio rerio) causes cystic kidneys: a nonmammalian model of polycystic kidney disease.Autosomal recessive polycystic kidney disease epithelial cell model reveals multiple basolateral epidermal growth factor receptor sorting pathways.Hippocampal and cortical primary cilia are required for aversive memory in mice.
P2860
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P2860
Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Polaris, a protein disrupted i ...... for assembly of renal cilium.
@en
type
label
Polaris, a protein disrupted i ...... for assembly of renal cilium.
@en
prefLabel
Polaris, a protein disrupted i ...... for assembly of renal cilium.
@en
P2093
P1476
Polaris, a protein disrupted i ...... for assembly of renal cilium.
@en
P2093
Albert Tousson
Bradley K Yoder
Charles E Bugg
Daniel F Balkovetz
James A Schafer
Leigh Millican
P304
P356
10.1152/AJPRENAL.00273.2001
P577
2002-03-01T00:00:00Z