Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.
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The organic anion transporter (OAT) family: a systems biology perspectiveRole of the Gut Microbiome in Uremia: A Potential Therapeutic Target.Inhibition of protein kinase CK2 prevents the progression of glomerulonephritisSubstrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions.The gut microbiome, kidney disease, and targeted interventions.Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1).Roles of organic anion transporters in the progression of chronic renal failure.Metabolomics and incident hypertension among blacks: the atherosclerosis risk in communities studySerum indoxyl sulfate is associated with vascular disease and mortality in chronic kidney disease patients.Renal Drug Transporters and Drug Interactions.Zeaxanthin, a retinal carotenoid, protects retinal cells against oxidative stress.Indoxyl sulfate, a uremic toxin in chronic kidney disease, suppresses both bone formation and bone resorption.Bioengineered kidney tubules efficiently excrete uremic toxins.Oral charcoal adsorbent (AST-120) prevents progression of cardiac damage in chronic kidney disease through suppression of oxidative stress.Acute uremia produced in rats by nephrotoxic chemicals is alleviated by protein deficient diet.Long-term effects of the oral adsorbent, AST-120, in patients with chronic renal failure.Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.Renal organic anion transporter 1 is maldistributed and diminishes in proximal tubule cells but increases in vasculature after ischemia and reperfusion.Biochemical and Clinical Impact of Organic Uremic Retention Solutes: A Comprehensive Update.Experimental models of renal dysfunction in female rats. Functional and histological aspects after unilateral nephrectomy or ligation of right renal vein with kidney preservation.Administration of oral charcoal adsorbent (AST-120) suppresses low-turnover bone progression in uraemic rats.A novel SNP in the 5' regulatory region of organic anion transporter 1 is associated with chronic kidney disease.
P2860
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P2860
Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Uraemic toxins induce proximal ...... transporter 1-mediated uptake.
@en
type
label
Uraemic toxins induce proximal ...... transporter 1-mediated uptake.
@en
prefLabel
Uraemic toxins induce proximal ...... transporter 1-mediated uptake.
@en
P2093
P2860
P356
P1476
Uraemic toxins induce proximal ...... transporter 1-mediated uptake.
@en
P2093
Atsuko Hosokawa
Hideyuki Yamato
Masaru Motojima
Takamura Muraki
Toshimasa Yoshioka
P2860
P304
P356
10.1038/SJ.BJP.0704482
P407
P577
2002-01-01T00:00:00Z