Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of th
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Genetic determinants and potential therapeutic targets for pancreatic adenocarcinomaThe ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translationApoptosis: targets in pancreatic cancerMolecular therapeutics in pancreas cancerThe Rise and the Fall of Betatrophin/ANGPTL8 as an Inducer of β-Cell ProliferationY-box-binding protein 1 confers EGF independence to human mammary epithelial cells.Insulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer.Biological approaches to therapy of pancreatic cancer.Tyrosine kinase pathways modulate tumor susceptibility to natural killer cellsExpression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma.Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia.Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer.Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis.Insulin and cancer.Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancerPersonalized therapy for pancreatic cancer: Myth or reality in 2010?Activation of insulin-like growth factor 1 receptor in patients with non-small cell lung cancer.Regulation of cyclooxygenase-2 (COX-2) expression in human pancreatic carcinoma cells by the insulin-like growth factor-I receptor (IGF-IR) system.Increased Serum Insulin Exposure Does Not Affect Age or Stage of Pancreatic Adenocarcinoma Diagnosis in Patients With Diabetes Mellitus.Hypoxia and angiogenesis in pancreatic cancer.Survival is associated with genetic variation in inflammatory pathway genes among patients with resected and unresected pancreatic cancer.Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.Molecular changes in pancreatic cancer.Emerging anticancer therapeutic targets and the cardiovascular system: is there cause for concern?The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer.HSP90 is a promising target in gemcitabine and 5-fluorouracil resistant pancreatic cancer.Insulin-like growth factor 1 receptor and p38 mitogen-activated protein kinase signals inversely regulate signal transducer and activator of transcription 3 activity to control human dental pulp stem cell quiescence, propagation, and differentiationGrowth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma.Insulin-like growth factor binding protein-5 influences pancreatic cancer cell growthInsulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta.Role of insulin receptor substrates and protein kinase C-zeta in vascular permeability factor/vascular endothelial growth factor expression in pancreatic cancer cells.Picropodophyllin (PPP) is a potent rhabdomyosarcoma growth inhibitor both in vitro and in vivoDual targeting of the insulin-like growth factor and collateral pathways in cancer: combating drug resistance.Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model.Expression of insulin-like growth factor-1 receptor, p-AKT and p-ERK1/2 protein in extramammary Paget's disease.Inhibition of insulin-like growth factor 1 receptor enhances the efficacy of sorafenib in inhibiting hepatocellular carcinoma cell growth and survival.The novel hsa-miR-12528 regulates tumourigenesis and metastasis through hypo-phosphorylation of AKT cascade by targeting IGF-1R in human lung cancer.
P2860
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P2860
Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of th
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Aberrant expression and activa ...... e and increased survival of th
@en
type
label
Aberrant expression and activa ...... e and increased survival of th
@en
prefLabel
Aberrant expression and activa ...... e and increased survival of th
@en
P2093
P2860
P356
P1433
P1476
Aberrant expression and activa ...... e and increased survival of th
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205044
P407
P577
2001-12-01T00:00:00Z
P5875
P6179
1050810710