Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis.
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Molecular targets of isothiocyanates in cancer: recent advancesBenzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteriaBenzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteBITC Sensitizes Pancreatic Adenocarcinomas to TRAIL-induced ApoptosisIdentification of potential protein targets of isothiocyanates by proteomicsNuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cellsBenzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.Macroautophagy: the key ingredient to a healthy diet?Proteins as binding targets of isothiocyanates in cancer prevention.Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesisCruciferous vegetables, isothiocyanates, and prevention of bladder cancer.Antimicrobial activities of isothiocyanates against Campylobacter jejuni isolates.Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implicationsAmiprophosmethyl-induced efficient in vitro production of polyploids in raphanobrassica with the aid of aminoethoxyvinylglycine (AVG) in the culture mediumVegetable-derived isothiocyanates: anti-proliferative activity and mechanism of action.Covalent binding to tubulin by isothiocyanates. A mechanism of cell growth arrest and apoptosis.Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.Role of reactive oxygen intermediates in cellular responses to dietary cancer chemopreventive agents.Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression.Insights into the mode of action of benzyl isothiocyanate on Campylobacter jejuni.Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.Electrophiles in foods: the current status of isothiocyanates and their chemical biology.Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells.Chemical alterations and regulations of biomolecules in lifestyle-related diseases.Mitochondrial dysfunction in cancer chemoprevention by phytochemicals from dietary and medicinal plants.Erucin and benzyl isothiocyanate suppress growth of late stage primary human ovarian carcinoma cells and telomerase activity in vitro.Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice.Allyl isothiocyanate depletes glutathione and upregulates expression of glutathione S-transferases in Arabidopsis thaliana.Benzyl isothiocyanate induces reactive oxygen species-initiated autophagy and apoptosis in human prostate cancer cells.Benzyl isothiocyanate disturbs lipid metabolism in rats in a way independent of its thyroid impact following in vivo long-term treatment and in vitro adipocytes studies.The protective role of Tropaeolum majus on blood and liver toxicity induced by diethyl maleate in rats.Mitochondrial respiratory chain involvement in peroxiredoxin 3 oxidation by phenethyl isothiocyanate and auranofin.Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk.(-)-Epigallocatechin-3-gallate potentiates the cytotoxicity induced by benzyl isothiocyanate and hydrogen peroxide in human Jurkat T lymphocytes.Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction.Determination of benzyl isothiocyanate metabolites in human plasma and urine by LC-ESI-MS/MS after ingestion of nasturtium (Tropaeolum majus L.).Physiological relevance of covalent protein modification by dietary isothiocyanates.Isothiocyanate E-4IB induces MAPK activation, delayed cell cycle transition and apoptosis.Isolation of tryptophol as an apoptosis-inducing component of vinegar produced from boiled extract of black soybean in human monoblastic leukemia U937 cells.
P2860
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P2860
Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Involvement of the mitochondri ...... thiocyanate-induced apoptosis.
@en
type
label
Involvement of the mitochondri ...... thiocyanate-induced apoptosis.
@en
prefLabel
Involvement of the mitochondri ...... thiocyanate-induced apoptosis.
@en
P2093
P2860
P356
P1476
Involvement of the mitochondri ...... thiocyanate-induced apoptosis.
@en
P2093
Akira Yoshihiro
Hajime Ohigashi
Kiyoshi Kawai
Koji Uchida
Makiko Kawakami
Noriyuki Miyoshi
Toshihiko Osawa
Yoshimasa Nakamura
P2860
P304
P356
10.1074/JBC.M109760200
P407
P577
2001-12-20T00:00:00Z