Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis. - Wikidata - wikimedia - TriplyDB

Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis.

Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis.

http://www.wikidata.org/entity/Q40768035

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Regulation of the multifunctional Ca2+/calmodulin-dependent protein kinase II by the PP2C phosphatase PPM1F in fibroblasts Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II Molecular mechanisms of microcystin toxicity in animal cells.Microcystin congener- and concentration-dependent induction of murine neuron apoptosis and neurite degeneration.The role of CaMKII in calcium-activated death pathways in bone marrow B cells.Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response.Dual mechanism of a natural CaMKII inhibitor Nodularin exposure induces SOD1 phosphorylation and disrupts SOD1 co-localization with actin filaments Negative regulation of multifunctional Ca2+/calmodulin-dependent protein kinases: physiological and pharmacological significance of protein phosphatases.Epithelial cell apoptosis causes acute lung injury masquerading as emphysema CaMKII in cerebral ischemia.Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.CaMKII in the cardiovascular system: sensing redox states.Aluminum Chloride Induces Osteoblasts Apoptosis via Disrupting Calcium Homeostasis and Activating Ca(2+)/CaMKII Signal Pathway.Cell Death Inducing Microbial Protein Phosphatase Inhibitors--Mechanisms of Action.CaMKII-γ mediates phosphorylation of BAD at Ser170 to regulate cytokine-dependent survival and proliferation.Mg2+- and MgATP-inhibited and Ca2+/calmodulin-sensitive TRPM7-like current in hepatoma and hepatocytes.Resistance to Fas-mediated apoptosis in malignant tumours is rescued by KN-93 and cisplatin via downregulation of c-FLIP expression and phosphorylation.Fortilin binds Ca2+ and blocks Ca2+-dependent apoptosis in vivo.The combination of calmodulin antagonists and interferon-gamma induces apoptosis through caspase-dependent and -independent pathways in cholangiocarcinoma cells.Glutamate-induced NFkappaB activation in the retina.Microcystins alter chemotactic behavior in Caenorhabditis elegans by selectively targeting the AWA sensory neuron.Association of genetic variation in calmodulin and left ventricular mass in full-term newborns.Quantitative proteomics analysis of zebrafish exposed to sub-lethal dosages of β-methyl-amino-L-alanine (BMAA).Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins.Oxidized CaMKII: a "heart stopper" for the sinus node?A novel, extraneuronal role for cyclin-dependent protein kinase 5 (CDK5): modulation of cAMP-induced apoptosis in rat leukemia cells.Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells.Characterization of the intracellular calcium store at the base of the sperm flagellum that regulates hyperactivated motility.CaM-kinaseII-dependent commitment to microcystin-induced apoptosis is coupled to cell budding, but not to shrinkage or chromatin hypercondensation.Residue-residue interactions regulating the Ca2+-induced EF-hand conformation changes in calmodulin.Identification of apoptosis-related genes and transcription variations in response to microcystin-LR in zebrafish liver.Intracellular Calcium Plays a Critical Role in the Microcystin-LR-Elicited Neurotoxicity Through PLC/IP3 Pathway.Subchronic microcystin-LR exposure increased hepatic apoptosis and induced compensatory mechanisms in mice.

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P2860

Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis.

http://www.wikidata.org/entity/Q40768035

description

2001 nî lūn-bûn

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2001年の論文

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年学术文章

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2001年學術文章

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2001年學術文章

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2001年學術文章

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name

Ca2+/calmodulin-dependent prot ...... microcystin-induced apoptosis.

@en

type

label

Ca2+/calmodulin-dependent prot ...... microcystin-induced apoptosis.

@en

prefLabel

Ca2+/calmodulin-dependent prot ...... microcystin-induced apoptosis.

@en

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P1433

Journal of Biological Chemistry

P1476

Ca2+/calmodulin-dependent prot ...... microcystin-induced apoptosis.

@en

P2093

Gunnar Mellgren

http://www.w3.org/2001/XMLSchema#string

Howard Schulman

http://www.w3.org/2001/XMLSchema#string

Kari E Fladmark

http://www.w3.org/2001/XMLSchema#string

Olav K Vintermyr

http://www.w3.org/2001/XMLSchema#string

Roald Boe

http://www.w3.org/2001/XMLSchema#string

P2860

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region

Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

Ca(2+)/CaM-dependent kinases: from activation to function

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1.

Establishment of okadaic acid resistant cell clones using a cDNA expression library.

Interactions between protein kinases and proteases in cellular signaling and regulation.

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

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2804-2811

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10.1074/JBC.M109049200

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4

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277

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Camilla Krakstad

Stein Ove Døskeland

Odd Terje Brustugun

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2001-11-16T00:00:00Z

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11713251

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P921

apoptotic process