Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment variable antibodies and saporin: in vitro results and in vivo effects in an acute rejection model.
about
Ribosome-inactivating proteins: from plant defense to tumor attackSaporin-S6: a useful tool in cancer therapy.Depleting syndecan-4+ T lymphocytes using toxin-bearing dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand: a new opportunity for treating activated T cell-driven diseaseSelective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporinImmunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity.Efficacy and toxicity of a CD22-targeted antibody-saporin conjugate in a xenograft model of non-Hodgkin's lymphomaImmunotoxins and other conjugates containing saporin-s6 for cancer therapy.Immunotoxins constructed with ribosome-inactivating proteins and their enhancers: a lethal cocktail with tumor specific efficacy.Hyperuricaemia, Xanthine Oxidoreductase and Ribosome-Inactivating Proteins from Plants: The Contributions of Fiorenzo Stirpe to Frontline Research.High-level expression of a functional humanized anti-CTLA4 single-chain variable fragment antibody in Pichia pastoris.CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction.The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20-expressing cells and produces a synergistic toxic effect with Fludarabine.ATG-saporin-S6 immunotoxin: a new potent and selective drug to eliminate activated lymphocytes and lymphoma cells.T-cell reconstitution without T-cell immunopathology in two models of T-cell-mediated tissue destruction.Isolation and enzymatic characterization of lamjapin, the first ribosome-inactivating protein from cryptogamic algal plant (Laminaria japonica A).Construction and characterization of a CTLA-4-targeted scFv-melittin fusion protein as a potential immunosuppressive agent for organ transplant.Expression of CTLA-4 in nonhuman primate lymphocytes and its use as a potential target for specific immunotoxin-mediated apoptosis: results of in vitro studies.CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis.
P2860
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P2860
Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment variable antibodies and saporin: in vitro results and in vivo effects in an acute rejection model.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Immunotoxins containing recomb ...... s in an acute rejection model.
@en
type
label
Immunotoxins containing recomb ...... s in an acute rejection model.
@en
prefLabel
Immunotoxins containing recomb ...... s in an acute rejection model.
@en
P2093
P50
P1476
Immunotoxins containing recomb ...... ts in an acute rejection model
@en
P2093
G B Ferrara
G L Palmisano
L Biancone
P L Tazzari
R M Lemoli
P304
P356
10.4049/JIMMUNOL.167.8.4222
P407
P577
2001-10-01T00:00:00Z